OBJECTIVE: To determine whether extremely low birth weight infants (ELBW) transfused at
lower hemoglobin thresholds versus higher thresholds have different rates of survival or …

Objective To establish the evidence of therapeutic hypothermia for newborns with hypoxic
ischemic encephalopathy (HIE). Data Sources Cochrane Central Register of Controlled Trials, …

Background. Previous reports of variations in outcomes among neonatal intensive care
units (NICUs) examined only specific subpopulations of interest (eg, very low birth weight [VLBW] …

Importance The goal of oxygen therapy is to deliver sufficient oxygen to the tissues while
minimizing oxygen toxicity and oxidative stress. It remains uncertain what values of arterial …

Importance Extremely preterm infants may experience intermittent hypoxemia or bradycardia
for many weeks after birth. The prognosis of these events is uncertain. Objective To …

Importance There are potential benefits and harms of hyperoxemia and hypoxemia for extremely
preterm infants receiving more vs less supplemental oxygen. Objective To compare the …

Objective: Previous studies that compared outcomes of infants born outside tertiary care
centers (outborn) with those born in tertiary care centers (inborn) did not account for admission …

BACKGROUND AND OBJECTIVE. Extremely low birth weight infants frequently receive red
cell transfusions. We sought to determine whether a restrictive versus liberal hemoglobin …

Objective: Significant evaporative heat loss in the very low birth weight infant can occur in the
delivery room. We investigated the effect of polyethylene wrap applied immediately at birth (…

Background The use of supplemental oxygen in the care of extremely preterm infants has
been common practice since the 1940s. Despite this, there is little agreement regarding which …