[HTML][HTML] Macrophage polarization in inflammatory diseases
YC Liu, XB Zou, YF Chai, YM Yao - International journal of …, 2014 - ncbi.nlm.nih.gov
Diversity and plasticity are two hallmarks of macrophages. M1 macrophages (classically
activated macrophages) are pro-inflammatory and have a central role in host defense …
activated macrophages) are pro-inflammatory and have a central role in host defense …
[HTML][HTML] Sepsis-induced cardiomyopathy: mechanisms and treatments
YC Liu, MM Yu, ST Shou, YF Chai - Frontiers in immunology, 2017 - frontiersin.org
Sepsis is a lethal syndrome with a high incidence and a weighty economy burden. The
pathophysiology of sepsis includes inflammation, immune dysfunction, and dysfunction of …
pathophysiology of sepsis includes inflammation, immune dysfunction, and dysfunction of …
[HTML][HTML] Recent advances in the molecular mechanisms underlying pyroptosis in sepsis
YL Gao, JH Zhai, YF Chai - Mediators of inflammation, 2018 - hindawi.com
Sepsis is recognized as a life-threatening organ dysfunctional disease that is caused by
dysregulated host responses to infection. Up to now, sepsis still remains a dominant cause …
dysregulated host responses to infection. Up to now, sepsis still remains a dominant cause …
Fullerenes with metals inside
Y Chai, T Guo, C Jin, RE Haufler… - The Journal of …, 1991 - ACS Publications
Fullerenes with a single lanthanum atom trapped on the inside of the carbon cagewere
produced by laser vaporizationof a lanthanum oxide/graphite composite rod in a flow of …
produced by laser vaporizationof a lanthanum oxide/graphite composite rod in a flow of …
[HTML][HTML] Association between age and clinical characteristics and outcomes of COVID-19
Y Liu, B Mao, S Liang, JW Yang, HW Lu… - European …, 2020 - Eur Respiratory Soc
The rapid outbreak of coronavirus disease 2019 (COVID-19) has been a matter of
international concern as the disease is spreading fast [1, 2]. Considering that the contagious …
international concern as the disease is spreading fast [1, 2]. Considering that the contagious …
Uranium Stabilization of C28: A Tetravalent Fullerene
T Guo, MD Diener, Y Chai, MJ Alford, RE Haufler… - Science, 1992 - science.org
Laser vaporization experiments with graphite in a supersonic cluster beam apparatus
indicate that the smallest fullerene to form in substantial abundance is C28. Although ab …
indicate that the smallest fullerene to form in substantial abundance is C28. Although ab …
[HTML][HTML] De novo design of protein interactions with learned surface fingerprints
Physical interactions between proteins are essential for most biological processes
governing life. However, the molecular determinants of such interactions have been …
governing life. However, the molecular determinants of such interactions have been …
[HTML][HTML] Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape
Z Zhao, J Zhou, M Tian, M Huang, S Liu, Y Xie… - Nature …, 2022 - nature.com
Omicron SARS-CoV-2 is rapidly spreading worldwide. To delineate the impact of emerging
mutations on spike's properties, we performed systematic structural analyses on apo …
mutations on spike's properties, we performed systematic structural analyses on apo …
[HTML][HTML] An unexpected N-terminal loop in PD-1 dominates binding by nivolumab
S Tan, H Zhang, Y Chai, H Song, Z Tong… - Nature …, 2017 - nature.com
Cancer immunotherapy by targeting of immune checkpoint molecules has been a research
'hot-spot'in recent years. Nivolumab, a human monoclonal antibody targeting PD-1, has …
'hot-spot'in recent years. Nivolumab, a human monoclonal antibody targeting PD-1, has …
Distribution of polycyclic aromatic hydrocarbons (PAHs) in Henan reach of the Yellow River, Middle China
The distribution and source of 16 polycyclic aromatic hydrocarbons (PAHs) in Henan Reach
of the Yellow River, Middle China, has been investigated.∑ PAHs levels ranged from 144.3 …
of the Yellow River, Middle China, has been investigated.∑ PAHs levels ranged from 144.3 …