User profiles for "author:Waqasuddin Khan"
 | Waqasuddin KhanAssistant Professor (Research), Department of Paediatrics and Child Health, The Agha … Verified email at aku.edu Cited by 393 |
Multiomic signals associated with maternal epidemiological factors contributing to preterm birth in low-and middle-income countries
Preterm birth (PTB) is the leading cause of death in children under five, yet comprehensive
studies are hindered by its multiple complex etiologies. Epidemiological associations …
studies are hindered by its multiple complex etiologies. Epidemiological associations …
Multiomics characterization of preterm birth in low-and middle-income countries
Importance Worldwide, preterm birth (PTB) is the single largest cause of deaths in the
perinatal and neonatal period and is associated with increased morbidity in young children …
perinatal and neonatal period and is associated with increased morbidity in young children …
[HTML][HTML] Higher entropy observed in SARS-CoV-2 genomes from the first COVID-19 wave in Pakistan
Background We investigated the genome diversity of SARS-CoV-2 associated with the early
COVID-19 period to investigate evolution of the virus in Pakistan. Materials and methods We …
COVID-19 period to investigate evolution of the virus in Pakistan. Materials and methods We …
[HTML][HTML] Identification of potential therapeutic intervening targets by in-silico analysis of nsSNPs in preterm birth-related genes
Prematurity is the foremost cause of death in children under 5 years of age. Genetics
contributes to 25–40% of all preterm births (PTB) yet we still need to identify specific targets …
contributes to 25–40% of all preterm births (PTB) yet we still need to identify specific targets …
Association of maternal prenatal selenium concentration and preterm birth: a multicountry meta-analysis
Background Selenium (Se), an essential trace mineral, has been implicated in preterm birth
(PTB). We aimed to determine the association of maternal Se concentrations during …
(PTB). We aimed to determine the association of maternal Se concentrations during …
Metabolic pathway analysis approach: identification of novel therapeutic target against methicillin resistant Staphylococcus aureus
Abstract Multiple Drug Resistant (MDR) bacteria are no more inhibited by the front line
antibiotics due to extreme resistance. Methicillin Resistant Staphylococcus aureus (MRSA) …
antibiotics due to extreme resistance. Methicillin Resistant Staphylococcus aureus (MRSA) …
[HTML][HTML] Predicting binding within disordered protein regions to structurally characterised peptide-binding domains
Disordered regions of proteins often bind to structured domains, mediating interactions
within and between proteins. However, it is difficult to identify a priori the short disordered …
within and between proteins. However, it is difficult to identify a priori the short disordered …
[HTML][HTML] Natural coumarins from Murraya paniculata as mixed-type inhibitors of cholinesterases: In vitro and in silico investigations
Currently, acetylcholinesterase (AChE) inhibiting drugs in clinical use, such as tacrine,
donepezil, rivastigmine, and galanthamine, are associated with serious side effects and …
donepezil, rivastigmine, and galanthamine, are associated with serious side effects and …
[HTML][HTML] Environmental surveillance for COVID-19 using SARS-CoV-2 RNA concentration in wastewater–a study in District East, Karachi, Pakistan
N Ansari, F Kabir, W Khan, F Khalid… - The Lancet Regional …, 2024 - thelancet.com
Background Wastewater-based surveillance is used to track the temporal patterns of the
SARS-CoV-2 virus in communities. Viral RNA particle detection in wastewater samples can …
SARS-CoV-2 virus in communities. Viral RNA particle detection in wastewater samples can …
[HTML][HTML] In silico modeling of the specific inhibitory potential of thiophene-2,3-dihydro-1,5-benzothiazepine against BChE in the formation of β-amyloid plaques …
Background Alzheimer's disease, known to be associated with the gradual loss of memory,
is characterized by low concentration of acetylcholine in the hippocampus and cortex part of …
is characterized by low concentration of acetylcholine in the hippocampus and cortex part of …