[HTML][HTML] Polygenic risk scores for disease risk prediction in Africa: current challenges and future directions
Early identification of genetic risk factors for complex diseases can enable timely
interventions and prevent serious outcomes, including mortality. While the genetics …
interventions and prevent serious outcomes, including mortality. While the genetics …
Diagnosis of pulmonary tuberculosis and assessment of treatment response through analyses of volatile compound patterns in exhaled breath samples
NM Zetola, C Modongo, O Matsiri, T Tamuhla… - Journal of Infection, 2017 - Elsevier
Objectives We determined the performance of a sensor array (an electronic nose) made of 8
metalloporphyrins coated quartz microbalances sensors for the diagnosis and prognosis of …
metalloporphyrins coated quartz microbalances sensors for the diagnosis and prognosis of …
A framework for the promotion of ethical benefit sharing in health research
A Bedeker, M Nichols, T Allie, T Tamuhla… - BMJ global …, 2022 - gh.bmj.com
There is an increasing recognition of the importance of including benefit sharing in research
programmes in order to ensure equitable and just distribution of the benefits arising from …
programmes in order to ensure equitable and just distribution of the benefits arising from …
[HTML][HTML] Coronavirus Host Genetics South Africa (COHG-SA) database—a variant database for gene regions associated with SARS-CoV-2 outcomes
F Barmania, J Mellet, MA Ryder, G Ford… - European Journal of …, 2022 - nature.com
The SARS-CoV-2 virus is responsible for the COVID-19 global public health emergency,
and the disease it causes is highly variable in its clinical presentation. Clinical phenotypes …
and the disease it causes is highly variable in its clinical presentation. Clinical phenotypes …
[HTML][HTML] Diabetes in a TB and HIV-endemic South African population: Analysis of a virtual cohort using routine health data
T Tamuhla, JA Dave, P Raubenheimer, N Tiffin - Plos one, 2021 - journals.plos.org
Background It is widely accepted that people living with diabetes (PLWD) are at increased
risk of infectious disease, yet there is a paucity of epidemiology studies on the relationship …
risk of infectious disease, yet there is a paucity of epidemiology studies on the relationship …
Multiple modes of data sharing can facilitate secondary use of sensitive health data for research
T Tamuhla, ET Lulamba, T Mutemaringa, N Tiffin - BMJ Global Health, 2023 - gh.bmj.com
Evidence-based healthcare relies on health data from diverse sources to inform decision-
making across different domains, including disease prevention, aetiology, diagnostics …
making across different domains, including disease prevention, aetiology, diagnostics …
[HTML][HTML] Identification of a large pool of microorganisms with an array of porphyrin based gas sensors
NM Zetola, C Modongo, K Matlhagela, E Sepako… - Sensors, 2016 - mdpi.com
The association between volatile compounds (VCs) and microorganisms, as demonstrated
by several studies, may offer the ground for a rapid identification of pathogens. To this …
by several studies, may offer the ground for a rapid identification of pathogens. To this …
[HTML][HTML] An e-consent framework for tiered informed consent for human genomic research in the global south, implemented as a REDCap template
T Tamuhla, N Tiffin, T Allie - BMC Medical Ethics, 2022 - Springer
Research involving human participants requires their consent, and it is common practice to
capture consent information on paper and store those hard copies, presenting issues such …
capture consent information on paper and store those hard copies, presenting issues such …
SufT is required for growth of Mycobacterium smegmatis under iron limiting conditions
T Tamuhla, L Joubert, D Willemse… - Microbiology, 2020 - microbiologyresearch.org
Iron-sulphur (FeS) clusters are versatile cofactors required for a range of biological
processes within cells. Due to the reactive nature of the constituent molecules, assembly …
processes within cells. Due to the reactive nature of the constituent molecules, assembly …
[HTML][HTML] Routine health data describe adherence and persistence patterns for oral diabetes medication for a virtual cohort in the Khayelitsha sub-district of Cape Town …
T Tamuhla, P Raubenheimer, JA Dave… - PLOS Global Public …, 2023 - journals.plos.org
Type 2 diabetes mellitus (T2DM) is managed with combined lifestyle modifications and
antidiabetic drugs, but people on treatment often fail to reach glycaemic control. Adherence …
antidiabetic drugs, but people on treatment often fail to reach glycaemic control. Adherence …