▪ Abstract The phosphoinositide 3-kinase (PI3K) family of enzymes is recruited upon growth
factor receptor activation and produces 3′ phosphoinositide lipids. The lipid products of …

The global nephrology community recognises the need for a cohesive plan to address the
problem of chronic kidney disease (CKD). In July, 2016, the International Society of …

BACKGROUND: There has been considerable interest in the hypothesis that low birth
weight may be a marker of impaired nephrogenesis and that this is causally related to …

A multiple case study was conducted in order to assess three leading theories of
developmental dyslexia:(i) the phonological theory,(ii) the magnocellular (auditory and …

Participation must be seen as political. There are always tensions underlying issues such as
who is involved, how, and on whose terms. While participation has the potential to challenge …

Hypoxia-inducible factor-1α (HIF-1α) 1 is a global transcriptional regulator of the hypoxic
response. Under normoxic conditions, HIF-1α is recognized by the von Hippel-Lindau tumor …

Adults with Asperger syndrome can understand mental states such as desires and beliefs
(mentalizing) when explicitly prompted to do so, despite having impairments in social …

Background The value of the individual placement and support (IPS) programme in helping
people with severe mental illness gain open employment is unknown in Europe. Our aim …

Difficulties in social cognition are well recognized in individuals with autism spectrum
conditions (henceforth 'autism'). Here we focus on one crucial aspect of social cognition: the …

The design of synthetic ligands that read the information stored in the DNA double helix has
been a long-standing goal at the interface of chemistry and biology,,,,. Cell-permeable small …