[HTML][HTML] BCG-induced trained immunity: history, mechanisms and potential applications

J Chen, L Gao, X Wu, Y Fan, M Liu, L Peng… - Journal of Translational …, 2023 - Springer
Abstract The Bacillus Calmette-Guérin (BCG) vaccine was discovered a century ago and
has since been clinically applicable. BCG can not only be used for the prevention of …

Global seroprevalence and sociodemographic characteristics of Borrelia burgdorferi sensu lato in human populations: a systematic review and meta-analysis

Y Dong, G Zhou, W Cao, X Xu, Y Zhang, Z Ji… - BMJ Global …, 2022 - gh.bmj.com
Introduction Borrelia burgdorferi sensu lato (Bb) infection, the most frequent tick-transmitted
disease, is distributed worldwide. This study aimed to describe the global seroprevalence …

[HTML][HTML] Human Brain Organoids as an In Vitro Model System of Viral Infectious Diseases

X Su, P Yue, J Kong, X Xu, Y Zhang, W Cao… - Frontiers in …, 2022 - frontiersin.org
Brain organoids, or brainoids, have shown great promise in the study of central nervous
system (CNS) infection. Modeling Zika virus (ZIKV) infection in brain organoids may help …

[HTML][HTML] Lung organoids as model to study SARS-CoV-2 infection

L Peng, L Gao, X Wu, Y Fan, M Liu, J Chen, J Song… - Cells, 2022 - mdpi.com
Coronavirus disease-2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has become a global pandemic and has severely affected …

Application of Droplet Digital PCR to Detection of Mycobacterium tuberculosis and Mycobacterium leprae Infections: A Narrative Review

Y Fan, J Chen, M Liu, X Xu, Y Zhang… - Infection and Drug …, 2022 - Taylor & Francis
Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis
(MTB) infection, which has seriously endangered human health for many years. With the …

[HTML][HTML] Antibiotic prophylaxis for prevention against Lyme disease following tick bite: an updated systematic review and meta-analysis

G Zhou, X Xu, Y Zhang, P Yue, S Luo, Y Fan… - BMC Infectious …, 2021 - Springer
Abstract Background In areas where Lyme disease is endemic, bites from ticks are common,
but no vaccine is currently available against Lyme disease for humans. Therefore, the …

Diels-Alder reactions of aza-and phospha-1, 3-butadienes with ethylene. An ab initio study

SM Bachrach, M Liu - The Journal of Organic Chemistry, 1992 - ACS Publications
Background (1) Experimental Motivations. While phosphaalkenes are a relatively new class
of organic compound, a number of phosphabutadienes have been prepared. The use of …

The intricate role of CCL5/CCR5 axis in Alzheimer disease

W Ma, A Liu, X Wu, L Gao, J Chen, H Wu… - … of Neuropathology & …, 2023 - academic.oup.com
The morbidity and mortality associated with Alzheimer disease (AD), one of the most
common neurodegenerative diseases, are increasing each year. Although both amyloid β …

Seventy years of evidence on the efficacy and safety of drugs for treating leprosy: a network meta-analysis

J Yang, J Kong, B Li, Z Ji, A Liu, J Chen, M Liu, Y Fan… - Journal of Infection, 2023 - Elsevier
Summary Objective The World Health Organization (WHO) recommends multidrug therapy
(MDT) with rifampicin, dapsone, and clofazimine for treating leprosy, which is based on very …

[HTML][HTML] Prevalence of Borrelia burgdorferi in Ixodidae Tick around Asia: A Systematic Review and Meta-Analysis

Z Ji, M Jian, P Yue, W Cao, X Xu, Y Zhang, Y Pan… - Pathogens, 2022 - mdpi.com
Lyme disease (LD) is a common arthropod-borne inflammatory disorder prevalent in the
northern hemisphere. LD is caused by a spirochete named Borrelia burgdorferi sl, which is …