Neglected tropical diseases

N Feasey, M Wansbrough-Jones… - British medical …, 2010 - academic.oup.com
Introduction The neglected tropical diseases (NTDs) are infectious diseases that principally
impact the world's poorest people. They have been neglected for decades, initially as part of …

[PDF][PDF] Mycobacterium ulcerans disease

TS van der Werf, Y Stienstra… - Bulletin of the World …, 2005 - SciELO Public Health
Mycobacterium ulcerans disease (Buruli ulcer) is an important health problem in several
west African countries. It is prevalent in scattered foci around the world, predominantly in …

Buruli ulcer: emerging from obscurity

M Wansbrough-Jones, R Phillips - The Lancet, 2006 - thelancet.com
Buruli ulcer is a skin disease caused by infection with Mycobacterium ulcerans, which
produces a potent toxin known as mycolactone, thus distinguishing itself from all other …

Effects of hydroxychloroquine on immune activation and disease progression among HIV-infected patients not receiving antiretroviral therapy: a randomized controlled …

NI Paton, RL Goodall, DT Dunn, S Franzen… - Jama, 2012 - jamanetwork.com
Context Therapies to decrease immune activation might be of benefit in slowing HIV disease
progression. Objective To determine whether hydroxychloroquine decreases immune …

[HTML][HTML] Rifampicin and clarithromycin (extended release) versus rifampicin and streptomycin for limited Buruli ulcer lesions: a randomised, open-label, non-inferiority …

RO Phillips, J Robert, KM Abass, W Thompson… - The Lancet, 2020 - thelancet.com
Background Buruli ulcer is a neglected tropical disease caused by Mycobacterium ulcerans
infection that damages the skin and subcutis. It is most prevalent in western and central …

Recent advances: role of mycolactone in the pathogenesis and monitoring of Mycobacterium ulcerans infection/Buruli ulcer disease

FS Sarfo, R Phillips, M Wansbrough‐Jones… - Cellular …, 2016 - Wiley Online Library
Infection of subcutaneous tissue with Mycobacterium ulcerans can lead to chronic skin
ulceration known as Buruli ulcer. The pathogenesis of this neglected tropical disease is …

Immunosuppressive Signature of Cutaneous Mycobacterium ulcerans Infection in the Peripheral Blood of Patients with Buruli Ulcer Disease

R Phillips, FS Sarfo, L Guenin-Macé… - The Journal of …, 2009 - academic.oup.com
Buruli ulcer disease (BUD) is an emerging human disease caused by infection with
Mycobacterium ulcerans which leads to the development of necrotic skin lesions. The …

Clinical and bacteriological efficacy of rifampin-streptomycin combination for two weeks followed by rifampin and clarithromycin for six weeks for treatment of …

RO Phillips, FS Sarfo, MK Abass, J Abotsi… - Antimicrobial agents …, 2014 - Am Soc Microbiol
Buruli ulcer, an ulcerating skin disease caused by Mycobacterium ulcerans infection, is
common in tropical areas of western Africa. We determined the clinical and microbiological …

[HTML][HTML] Mycolactone diffuses into the peripheral blood of buruli ulcer patients-implications for diagnosis and disease monitoring

FS Sarfo, F Le Chevalier, NG Aka… - PLoS neglected …, 2011 - journals.plos.org
Background Mycobacterium ulcerans, the causative agent of Buruli ulcer (BU), is unique
among human pathogens in its capacity to produce a polyketide-derived macrolide called …

[HTML][HTML] Kinetics of mycolactone in human subcutaneous tissue during antibiotic therapy for Mycobacterium ulcerans disease

FS Sarfo, RO Phillips, J Zhang, MK Abass… - BMC infectious …, 2014 - Springer
Background Mycobacterium ulcerans (M. ulcerans) causes a devastating necrotising
infection of skin tissue leading to progressive ulceration. M. ulcerans is the only human …