Tumors develop multiple mechanisms of immune evasion as they progress, with some
cancer types being inherently better at 'hiding'than others. With an increased understanding …

Background Although numerous mouse models of breast carcinomas have been developed,
we do not know the extent to which any faithfully represent clinically significant human …

RANK and RANKL, a receptor ligand pair belonging to the tumour necrosis factor family, are
the critical regulators of osteoclast development and bone metabolism. Besides their …

Breast cancer is the most common female cancer, affecting approximately one in eight
women during their life-time. Besides environmental triggers and hormones, inherited …

The progesterone receptor (PR) plays roles in normal mammary development and breast
cancer formation, where it may exert both stimulatory and inhibitory actions. Previously, the …

Introduction Power relations permeate research partnerships and compromise the ability of
participatory research approaches to bring about transformational and sustainable change …

Background Breast cancer is the second most lethal cancer in women. Understanding
biological mechanisms that cause progression of this disease could yield new targets for …

Loss of full-length Brca1 in mammary epithelial cells of the mouse mammary tumor virus
(MMTV)-Cre Brca1 conditional exon 11 deletion mouse model results in the development of …

A major challenge to breast cancer research is the identification of alterations in the
architecture and composition of the breast that are associated with breast cancer …

Online research methods have risen in popularity over recent decades, particularly in the
wake of COVID-19. We conducted five online workshops capturing the experiences of …