User profiles for "author:José Lourenço"
 | José LourençoRA @ University of Oxford | PI, Prof @ Universidade Católica Portuguesa Verified email at ucp.pt Cited by 9363 |
[HTML][HTML] Estimating the false-negative test probability of SARS-CoV-2 by RT-PCR
Background Reverse-transcription PCR (RT-PCR) assays are used to test for infection with
the SARS-CoV-2 virus. RT-PCR tests are highly specific and the probability of false positives …
the SARS-CoV-2 virus. RT-PCR tests are highly specific and the probability of false positives …
[PDF][PDF] HIV-1 and SARS-CoV-2: Patterns in the evolution of two pandemic pathogens
Humanity is currently facing the challenge of two devastating pandemics caused by two very
different RNA viruses: HIV-1, which has been with us for decades, and SARS-CoV-2, which …
different RNA viruses: HIV-1, which has been with us for decades, and SARS-CoV-2, which …
[HTML][HTML] Detection of a SARS-CoV-2 variant of concern in South Africa
Continued uncontrolled transmission of SARS-CoV-2 in many parts of the world is creating
conditions for substantial evolutionary changes to the virus,. Here we describe a newly …
conditions for substantial evolutionary changes to the virus,. Here we describe a newly …
Emergence and rapid spread of a new severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) lineage with multiple spike mutations in South Africa
Continued uncontrolled transmission of the severe acute respiratory syndrome-related
coronavirus 2 (SARS-CoV-2) in many parts of the world is creating the conditions for …
coronavirus 2 (SARS-CoV-2) in many parts of the world is creating the conditions for …
[HTML][HTML] Global SARS-CoV-2 genomic surveillance: What we have learned (so far)
The COVID-19 pandemic has brought significant challenges for genomic surveillance
strategies in public health systems worldwide. During the past thirty-four months, many …
strategies in public health systems worldwide. During the past thirty-four months, many …
Zika virus in the Americas: early epidemiological and genetic findings
Brazil has experienced an unprecedented epidemic of Zika virus (ZIKV), with~ 30,000 cases
reported to date. ZIKV was first detected in Brazil in May 2015, and cases of microcephaly …
reported to date. ZIKV was first detected in Brazil in May 2015, and cases of microcephaly …
[HTML][HTML] Sixteen novel lineages of SARS-CoV-2 in South Africa
The first severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in South
Africa was identified on 5 March 2020, and by 26 March the country was in full lockdown …
Africa was identified on 5 March 2020, and by 26 March the country was in full lockdown …
[HTML][HTML] Genomic epidemiology of the SARS-CoV-2 epidemic in Brazil
The high numbers of COVID-19 cases and deaths in Brazil have made Latin America an
epicentre of the pandemic. SARS-CoV-2 established sustained transmission in Brazil early …
epicentre of the pandemic. SARS-CoV-2 established sustained transmission in Brazil early …
[HTML][HTML] Measuring the effects of COVID-19-related disruption on dengue transmission in southeast Asia and Latin America: a statistical modelling study
Background The COVID-19 pandemic has resulted in unprecedented disruption to society,
which indirectly affects infectious disease dynamics. We aimed to assess the effects of …
which indirectly affects infectious disease dynamics. We aimed to assess the effects of …
Fundamental principles of epidemic spread highlight the immediate need for large-scale serological surveys to assess the stage of the SARS-CoV-2 epidemic
J Lourenço, R Paton, M Ghafari, M Kraemer… - MedRxiv, 2020 - medrxiv.org
The spread of a novel pathogenic infectious agent eliciting protective immunity is typically
characterised by three distinct phases:(I) an initial phase of slow accumulation of new …
characterised by three distinct phases:(I) an initial phase of slow accumulation of new …