Onchocerciasis‐associated epilepsy: From recent epidemiological and clinical findings to policy implications

R Colebunders, AK Njamnshi, M van Oijen… - Epilepsia …, 2017 - Wiley Online Library
A high prevalence of epilepsy is reported in many onchocerciasis‐endemic regions. In this
paper we discuss recent epidemiological and clinical aspects as well as public health …

[HTML][HTML] The art of writing and implementing standard operating procedures (SOPs) for laboratories in low-resource settings: review of guidelines and best practices

B Barbé, K Verdonck, D Mukendi, V Lejon… - PLoS neglected …, 2016 - journals.plos.org
For a clinical study in the European research network on better diagnosis for neglected
infectious diseases (NIDIAG) project (Better Diagnosis of Neglected Infectious Diseases …

[HTML][HTML] Onchocerciasis-associated epilepsy in the Democratic Republic of Congo: Clinical description and relationship with microfilarial density

JN Siewe Fodjo, M Mandro, D Mukendi… - PLoS neglected …, 2019 - journals.plos.org
Background High epilepsy prevalence and incidence were observed in onchocerciasis-
endemic villages in the Democratic Republic of Congo (DRC). We investigated the clinical …

[HTML][HTML] High prevalence of epilepsy in onchocerciasis endemic health areas in Democratic Republic of the Congo

E Lenaerts, M Mandro, D Mukendi… - Infectious Diseases of …, 2018 - Springer
Background A high prevalence of epilepsy has been observed in many onchocerciasis
endemic regions. This study is to estimate the prevalence of active epilepsy and exposure to …

[HTML][HTML] High prevalence of epilepsy in an onchocerciasis endemic health zone in the Democratic Republic of the Congo, despite 14 years of community-directed …

D Mukendi, F Tepage, I Akonda, JNF Siewe… - International Journal of …, 2019 - Elsevier
Objectives To investigate the reasons for the high prevalence of epilepsy (> 6%) discovered
in 2015 in the Aketi health zone in the north of the Democratic Republic of the Congo …

[HTML][HTML] Ivermectin as an adjuvant to anti-epileptic treatment in persons with onchocerciasis-associated epilepsy: A randomized proof-of-concept clinical trial

M Mandro, JN Siewe Fodjo, D Mukendi… - PLoS neglected …, 2020 - journals.plos.org
Introduction Recent findings from onchocerciasis-endemic foci uphold that increasing
ivermectin coverage reduces the epilepsy incidence, and anecdotal evidence suggests …

[HTML][HTML] Single versus multiple dose ivermectin regimen in onchocerciasis-infected persons with epilepsy treated with phenobarbital: a randomized clinical trial in the …

M Mandro, JN Siewe Fodjo, A Dusabimana, D Mukendi… - Pathogens, 2020 - mdpi.com
Background: There is anecdotal evidence that ivermectin may decrease seizure frequency
in Onchocerca volvulus-infected persons with epilepsy (PWE). Methods: In October 2017, a …

[HTML][HTML] A phase III diagnostic accuracy study of a rapid diagnostic test for diagnosis of second-stage human African trypanosomiasis in the Democratic Republic of the …

M Boelaert, D Mukendi, E Bottieau, JRK Lilo… - …, 2018 - thelancet.com
Objectives To estimate the diagnostic accuracy of HAT Sero K-SeT for the field diagnosis of
second-stage human African trypanosomiasis (HAT). Design A phase III diagnostic accuracy …

[HTML][HTML] Antibiotic use prior to seeking medical care in patients with persistent fever: a cross-sectional study in four low-and middle-income countries

B Ingelbeen, KD Koirala, K Verdonck, B Barbé… - Clinical Microbiology …, 2021 - Elsevier
Objectives Community-level antibiotic use contributes to antimicrobial resistance, but is
rarely monitored as part of efforts to optimize antibiotic use in low-and middle-income …

[HTML][HTML] Ivermectin treatment in patients with onchocerciasis-associated epilepsy: protocol of a randomized clinical trial

R Colebunders, M Mandro, D Mukendi… - JMIR research …, 2017 - researchprotocols.org
Background: Many studies have reported an association between epilepsy, nodding
syndrome (NS), and onchocerciasis (river blindness). A high prevalence of epilepsy has …