User profiles for "author:Carlota Dobaño"

Carlota Dobaño

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Cited by 9587

Acquired immunity to malaria

DL Doolan, C Dobaño, JK Baird - Clinical microbiology reviews, 2009 - Am Soc Microbiol
Naturally acquired immunity to falciparum malaria protects millions of people routinely
exposed to Plasmodium falciparum infection from severe disease and death. There is no …

[HTML][HTML] Improving vaccine-induced immunity: can baseline predict outcome?

JS Tsang, C Dobaño, P VanDamme, G Moncunill… - Trends in …, 2020 - cell.com
Immune signatures measured at baseline and immediately prior to vaccination may predict
the immune response to vaccination. Such pre-vaccine assessment might allow not only …

Challenges and strategies for developing efficacious and long-lasting malaria vaccines

JG Beeson, L Kurtovic, C Dobaño, DH Opi… - Science translational …, 2019 - science.org
Although there has been major recent progress in malaria vaccine development, substantial
challenges remain for achieving highly efficacious and durable vaccines against …

[HTML][HTML] Seroprevalence of antibodies against SARS-CoV-2 among health care workers in a large Spanish reference hospital

AL Garcia-Basteiro, G Moncunill, M Tortajada… - Nature …, 2020 - nature.com
Health care workers (HCW) are a high-risk population to acquire SARS-CoV-2 infection from
patients or other fellow HCW. This study aims at estimating the seroprevalence against …

[HTML][HTML] The effect of early treatment with ivermectin on viral load, symptoms and humoral response in patients with non-severe COVID-19: A pilot, double-blind …

C Chaccour, A Casellas, A Blanco-Di Matteo… - …, 2021 - thelancet.com
Background Ivermectin inhibits the replication of SARS-CoV-2 in vitro at concentrations not
readily achievable with currently approved doses. There is limited evidence to support its …

[HTML][HTML] Genetic diversity and protective efficacy of the RTS, S/AS01 malaria vaccine

DE Neafsey, M Juraska, T Bedford… - … England Journal of …, 2015 - Mass Medical Soc
Background The RTS, S/AS01 vaccine targets the circumsporozoite protein of Plasmodium
falciparum and has partial protective efficacy against clinical and severe malaria disease in …

[HTML][HTML] Seven-month kinetics of SARS-CoV-2 antibodies and role of pre-existing antibodies to human coronaviruses

N Ortega, M Ribes, M Vidal, R Rubio, R Aguilar… - Nature …, 2021 - nature.com
Unraveling the long-term kinetics of antibodies to SARS-CoV-2 and the individual
characteristics influencing it, including the impact of pre-existing antibodies to human …

[HTML][HTML] An autopsy study of maternal mortality in Mozambique: the contribution of infectious diseases

C Menendez, C Romagosa, MR Ismail, C Carrilho… - PLoS …, 2008 - journals.plos.org
Background Maternal mortality is a major health problem concentrated in resource-poor
regions. Accurate data on its causes using rigorous methods is lacking, but is essential to …

Impact of severe acute respiratory syndrome coronavirus 2 infection on pregnancy outcomes: a population-based study

F Crovetto, F Crispi, E Llurba, R Pascal… - Clinical Infectious …, 2021 - academic.oup.com
Background We performed a population-based study to describe the impact of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on pregnancy outcomes …

[HTML][HTML] Determinants of early antibody responses to COVID-19 mRNA vaccines in a cohort of exposed and naïve healthcare workers

G Moncunill, R Aguilar, M Ribes, N Ortega, R Rubio… - …, 2022 - thelancet.com
Background Two doses of mRNA vaccination have shown> 94% efficacy at preventing
COVID-19 mostly in naïve adults, but it is not clear if the second dose is needed to maximize …