[HTML][HTML] Novel stepwise approach to assess representativeness of a large multicenter observational cohort of tuberculosis patients: the example of RePORT Brazil

MB Arriaga, G Amorim, ATL Queiroz… - International Journal of …, 2021 - Elsevier
Background A major goal of tuberculosis (TB) epidemiologic studies is to obtain results that
can be generalized to the larger population with TB. The ability to extrapolate findings on …

The Xpert MTB/RIF Cycle Threshold Value Predicts Mycobacterium tuberculosis Transmission to Close Contacts in a Brazilian Prospective Multicenter Cohort

LS Garcia, AG Costa, M Araújo-Pereira… - Clinical Infectious …, 2024 - academic.oup.com
Abstract Background The Xpert MTB/RIF rapid molecular test provides a quantitative
measure of Mycobacterium tuberculosis (Mtb) DNA in the form of cycle threshold (Ct) values …

Determinants of losses in the latent tuberculosis infection cascade of care in Brazil

AB Souza, MB Arriaga, G Amorim, M Araújo-Pereira… - BMJ global …, 2021 - gh.bmj.com
Introduction Factors associated with losses in the latent tuberculosis infection (LTBI)
cascade of care in contacts of patients with tuberculosis (TB) were investigated in a …

[HTML][HTML] Pre-treatment neutrophil count as a predictor of antituberculosis therapy outcomes: a multicenter prospective cohort study

ACC Carvalho, G Amorim, MGM Melo… - Frontiers in …, 2021 - frontiersin.org
Background Neutrophils have been associated with lung tissue damage in many diseases,
including tuberculosis (TB). Whether neutrophil count can serve as a predictor of adverse …

Lessons learned from implementation of an interferon gamma release assay to screen for latent tuberculosis infection in a large multicenter observational cohort study …

AG Costa, BKS Carvalho, M Araújo-Pereira… - Microbiology …, 2021 - Am Soc Microbiol
The interferon gamma release assay (IGRA) has emerged as a useful tool for identifying
latent tuberculosis infection (LTBI). This assay can be performed through testing platforms …

Polymorphisms in TLR4 and TNFA and Risk of Mycobacterium tuberculosis Infection and Development of Active Disease in Contacts of Tuberculosis Cases in Brazil …

JM Cubillos-Angulo, MB Arriaga… - Clinical Infectious …, 2019 - academic.oup.com
Background The role of genetic polymorphisms in latent tuberculosis (TB) infection and
progression to active TB is not fully understood. Methods We tested the single-nucleotide …

[HTML][HTML] Polymorphisms in interferon pathway genes and risk of Mycobacterium tuberculosis infection in contacts of tuberculosis cases in Brazil

JM Cubillos-Angulo, MB Arriaga, MGM Melo… - International Journal of …, 2020 - Elsevier
Background Host genetic polymorphisms may be important in determining susceptibility to
Mycobacterium tuberculosis (Mtb) infection, but their role is not fully understood. Detection of …

[HTML][HTML] Anemia and anti-tuberculosis treatment outcome in persons with pulmonary tuberculosis: A multi-center prospective cohort study

M Araújo-Pereira, BMF Nogueira… - Journal of infection and …, 2023 - Elsevier
Background Tuberculosis (TB) remains a major plague of humanity. People with TB (PWTB)
are commonly anemic. Here, we assessed whether the severity of anemia in PWTB prior to …

[HTML][HTML] Prevalence and clinical profiling of dysglycemia and HIV infection in persons with pulmonary tuberculosis in Brazil

MB Arriaga, M Araújo-Pereira, B Barreto-Duarte… - Frontiers in …, 2022 - frontiersin.org
Background There are scarce data on the prevalence and disease presentation of HIV in
patients with tuberculosis (TB) and dysglycemia (diabetes [DM] and prediabetes [PDM]) …

Determinants of losses in the latent tuberculosis infection cascade of care in Brazil: a prospective multicenter cohort study

AB Souza, M B. Arriaga, G Amorim, M Araújo-Pereira… - medRxiv, 2021 - medrxiv.org
Background Factors associated with losses in the latent tuberculosis infection (LTBI)
cascade of care in contacts of tuberculosis (TB) patients were investigated in a multicenter …