Diagnosis of henipavirus infection: current capabilities and future directions

Curr Top Microbiol Immunol. 2012:359:179-96. doi: 10.1007/82_2012_215.

Abstract

Since the last major review on diagnosis of henipavirus infection about a decade ago, significant progress has been made in many different areas of test development, especially in the development of molecular tests using real-time PCR and many novel serological test platforms. In addition to provide an updated review of the current test capabilities, this review also identifies key future challenges in henipavirus diagnosis.

Publication types

  • Review

MeSH terms

  • Animals
  • Cell Line
  • Enzyme-Linked Immunosorbent Assay
  • Hendra Virus / genetics
  • Hendra Virus / isolation & purification*
  • Hendra Virus / pathogenicity
  • Henipavirus Infections / blood
  • Henipavirus Infections / cerebrospinal fluid
  • Henipavirus Infections / diagnosis*
  • Henipavirus Infections / virology
  • Humans
  • Immunohistochemistry
  • Microscopy, Electron
  • Molecular Typing
  • Neutralization Tests
  • Nipah Virus / genetics
  • Nipah Virus / isolation & purification*
  • Nipah Virus / pathogenicity
  • Real-Time Polymerase Chain Reaction