[Study of 71 cases of visceral leishmaniasis diagnosed at the Mustapha University Hospital (Algiers) from 1998 to 2009]

Med Mal Infect. 2012 Mar;42(3):119-25. doi: 10.1016/j.medmal.2012.01.001. Epub 2012 Feb 16.
[Article in French]

Abstract

Objective: The authors retrospectively studied the epidemiological, clinical, diagnostic and therapeutic aspects of 71 cases of visceral leishmaniasis from 1998 to 2009.

Population and methods: The diagnosis was made by finding Leishmania amastigotes in bone marrows smears and/or by serology.

Results: Most cases occur in winter (35.2%) and in spring (36.6%). The source areas are endemic ones located in the north of Algeria (74.6%) and more rarely arid or semi-arid climate areas (8.4%). 88.7% of patients are children. The sex ratio is 1.53. The clinical characteristics are: fever (77.4%), paleness (43.6%); splenomegaly (83%), hepatomegaly (57.7%). The biological anomalies are: anemia (56.3%), thrombocytopenia (33.8%), and leucopenia (28.1%). N-methylglucamine (Glucantime(®)) was most often prescribed (70.4%). Four deaths (5.6%) were recorded.

Conclusion: Visceral leishmaniasis remains a pediatric affection but does not spare adults.

Publication types

  • English Abstract

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Algeria / epidemiology
  • Animals
  • Antiprotozoal Agents / therapeutic use
  • Bone Marrow / parasitology
  • Child
  • Child, Preschool
  • Dog Diseases / epidemiology
  • Dog Diseases / parasitology
  • Dogs / parasitology
  • Endemic Diseases
  • Hospitals, University / statistics & numerical data*
  • Humans
  • Infant
  • Insect Vectors / parasitology
  • Leishmania infantum / isolation & purification
  • Leishmaniasis, Visceral / diagnosis
  • Leishmaniasis, Visceral / epidemiology*
  • Leishmaniasis, Visceral / transmission
  • Leishmaniasis, Visceral / veterinary
  • Middle Aged
  • Phlebotomus / parasitology
  • Retrospective Studies
  • Sex Distribution
  • Young Adult
  • Zoonoses

Substances

  • Antiprotozoal Agents