Abstract
Multidrug-resistant tuberculosis (MDR-TB) is a growing problem in China. In 2008, all smear-positive pulmonary TB patients in a city in northern China were expected to undergo routine culture and drug susceptibility testing (DST). We assessed the performance of this system. There were 915 patients, of whom 356 (39%) had culture performed; 275 (30%) had positive cultures and 236 (26%) had DST. Of the 236 patients with DST, 6% of new and 32% of previously treated patients had MDR-TB. Culture and DST is an important service for the correct management of patients, and solutions to improve the current system need to be considered.
Publication types
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Evaluation Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Aged
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Aged, 80 and over
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Antitubercular Agents / therapeutic use*
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Bacteriological Techniques*
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Chi-Square Distribution
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China
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Drug Resistance, Multiple, Bacterial*
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Female
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Humans
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Male
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Microbial Sensitivity Tests*
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Middle Aged
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Mycobacterium tuberculosis / drug effects*
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Mycobacterium tuberculosis / growth & development
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Mycobacterium tuberculosis / isolation & purification
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Predictive Value of Tests
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Sputum / microbiology
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Tuberculosis, Multidrug-Resistant / diagnosis*
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Tuberculosis, Multidrug-Resistant / drug therapy
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Tuberculosis, Multidrug-Resistant / microbiology
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Tuberculosis, Pulmonary / diagnosis*
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Tuberculosis, Pulmonary / drug therapy
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Tuberculosis, Pulmonary / microbiology
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Young Adult