Viral load as predictor of Crimean-Congo hemorrhagic fever outcome

Emerg Infect Dis. 2007 Nov;13(11):1769-72. doi: 10.3201/eid1311.070222.

Abstract

We used quantitative real-time reverse transcription-PCR to measure viral load in serum from 24 patients in Kosovo who had acute Crimean-Congo hemorrhagic fever. Viral load correlated with clinical disease and antibodies and could be used as a predictor of disease outcome.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Enzyme-Linked Immunosorbent Assay
  • Hemorrhagic Fever Virus, Crimean-Congo / isolation & purification*
  • Hemorrhagic Fever, Crimean / immunology
  • Hemorrhagic Fever, Crimean / virology*
  • Humans
  • Immunoglobulin G / blood
  • Immunoglobulin M / blood
  • Reverse Transcriptase Polymerase Chain Reaction
  • Viral Load
  • Yugoslavia

Substances

  • Immunoglobulin G
  • Immunoglobulin M