Antiretroviral drug content in products from developing countries

Clin Infect Dis. 2004 May 1;38(9):1317-9. doi: 10.1086/383575. Epub 2004 Apr 14.

Abstract

Generic and brand name antiretroviral drugs are becoming increasingly available in developing countries. We analyzed 6 antiretroviral medications from 4 international sources for drug content. The active ingredient in tested drug products was within 15% of the labeled amount (range, -12% to +15%) for drugs that were properly stored.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Anti-Retroviral Agents / analysis*
  • Anti-Retroviral Agents / chemistry
  • Biological Availability
  • Developing Countries*
  • Drug Industry
  • Drugs, Generic / analysis*
  • Drugs, Generic / chemistry
  • Humans
  • Therapeutic Equivalency*

Substances

  • Anti-Retroviral Agents
  • Drugs, Generic