Table 2

Costs borne by TB-affected households averted and number of households with catastrophic costs averted by adolescent/adult tuberculosis vaccines (in millions)

Country groupingDirect medical costs borne by TB-affected households avertedDirect non-medical costs borne by TB-affected households avertedIndirect costs borne by TB-affected households avertedTotal costs borne by TB-affected households avertedNumber of households with catastrophic costs averted
All countries7252 (6758–7755)14 987 (13 999–16 044)16 620 (15 574–17 858)38 860 (36 594–41 461)22.9 (21.4–24.5)
High-TB burden*5524 (5078–5956)12 879 (11 895–13 896)13 701 (12 699–14 820)32 103 (29 894–34 544)20.2 (18.7–21.8)
High-TB/HIV burden*3807 (3449–4185)10 719 (9803–11 698)11 507 (10 547–12 597)26 033 (23 851–28 389)17.3 (15.8–18.8)
High-MDR/RR-TB burden*5614 (5163–6103)11 676 (10 733–12 687)12 588 (11 605–13 676)29 878 (27 590–32 293)17.9 (16.4–19.4)
Income level†
LIC876 (770–998)1686 (1533–1849)2842 (2494–3221)5405 (4812–6034)3.31 (3.02–3.62)
LMIC4146 (3759–4547)10 628 (9663–11 593)9449 (8627–10 315)24 223 (22 111–26 293)17.3 (15.8–18.8)
UMIC2230 (2002–2481)2673 (2464–2899)4329 (3774–4905)9232 (8388–10 066)2.25 (2.01–2.50)
World region
AFR2126 (1933–2336)5084 (4684–5500)6597 (5968–7268)13 808 (12 713–15 014)8.52 (7.93–9.16)
AMR415 (370–461)530 (489–572)513 (472–558)1458 (1349–1568)0.30 (0.28–0.32)
EMR846 (717–988)1410 (1170–1651)2161 (1801–2557)4418 (3734–5169)2.35 (1.92–2.83)
EUR428 (364–507)219 (196–243)300 (263–341)947 (830–1078)0.15 (0.13–0.17)
SEAR1689 (1410–1997)5638 (4829–6510)4362 (3696–5071)11 689 (9952–13 516)8.94 (7.68–10.3)
WPR1748 (1546–1967)2105 (1905–2323)2686 (2368–3034)6539 (5907–7246)2.63 (2.29–3.04)
  • All countries include 105 low- and middle-income countries analysed.

  • Values in parentheses represent equal-tailed 95% credible intervals. Total costs included patient direct medical, direct non-medical, and indirect costs (all undiscounted) over 2028–2050 in 2020 USD. Catastrophic costs are defined as instances where the total patient costs (direct medical, direct non-medical and indirect) incurred during an episode of TB disease exceeded 20% of total annual household income.

  • *High-TB, high-TB/HIV (HIV-associated TB), and high-MDR/RR-TB (multidrug/rifampicin-resistant TB) burden countries as defined by the WHO.

  • †LIC: gross national income (GNI) per capita of US$1085 or less; LMIC: GNI per capita of US$1086–4225; UMIC: GNI per capita of US$4256–13 205.26

  • AFR, African region; AMR, region of the Americas; EMR, Eastern Mediterranean region; EUR, European region; GDP, gross domestic product; LIC, low-income country; LMIC, lower middle-income country; SEAR, Southeast Asian region; TB, tuberculosis; UMIC, upper middle-income country; WPR, Western Pacific region.