Pathogen-specific attributable incidence with 95% CIs of diarrhoea hospitalisations and deaths in 2017–2018 both globally and by geographic grouping in children less than 5 years of age in Global Pediatric Diarrhea Surveillance countries
All cause | Rotavirus | Shigella | Norovirus | Adenovirus 40/41 | Sapovirus | ETEC | Cryptosporidium | Astrovirus | C. jejuni/C. coli | Salmonella | |
Hospitalisations* | 19.2 (17.0 to 21.9) | 6.4 (5.3 to 7.8) | 1.9 (1.5 to 2.2) | 1.2 (1.0 to 1.5) | 1.1 (0.8 to 1.3) | 0.7 (0.6 to 0.9) | 0.7 (0.6 to 0.9) | 0.7 (0.5 to 0.8) | 0.5 (0.4 to 0.7) | 0.3 (0.2 to 0.4) | 0.2 (0.1 to 0.3) |
Central America | 17.2 (13.2 to 22.3) | 3.0 (2.2 to 4.0) | 3.3 (1.9 to 4.8) | 2.0 (1.0 to 3.5) | 1.7 (0.7 to 2.6) | 0.5 (0.2 to 0.8) | 0.4 (0.2 to 0.6) | 0.3 (0.1 to 0.5) | 0.8 (0.4 to 1.2) | 0.5 (0.0 to 0.8) | 0.1 (0.0 to 0.1) |
South America | 10.8 (8.9 to 13.1) | 1.7 (1.3 to 2.2) | 1.3 (1.0 to 1.6) | 2.4 (1.9 to 3.0) | 0.6 (0.4 to 0.8) | 0.5 (0.4 to 0.6) | 0.3 (0.2 to 0.4) | 0.1 (0.0 to 0.1) | 0.2 (0.1 to 0.2) | 0.3 (0.2 to 0.4) | 0.1 (0.0 to 0.1) |
Eastern Europe | 3.9 (2.8 to 5.4) | 1.4 (1.0 to 2.1) | 0.0 (0.0 to 0.0) | 0.3 (0.2 to 0.4) | 0.1 (0.0 to 0.1) | 0.1 (0.1 to 0.1) | 0.0 (0.0 to 0.0) | 0.0 (0.0 to 0.0) | 0.0 (0.0 to 0.0) | 0.2 (0.1 to 0.3) | 0.1 (0.0 to 0.1) |
Central and Western Asia | 4.4 (3.4 to 5.6) | 0.7 (0.5 to 0.9) | 0.4 (0.3 to 0.5) | 0.5 (0.4 to 0.7) | 0.1 (0.1 to 0.2) | 0.3 (0.2 to 0.3) | 0.2 (0.1 to 0.2) | 0.1 (0.1 to 0.1) | 0.1 (0.1 to 0.2) | 0.0 (0.0 to 0.0) | 0.0 (0.0 to 0.0) |
West Africa | 61.3 (48.0 to 78.4) | 27.5 (19.7 to 36.9) | 5.8 (3.1 to 7.8) | 2.6 (1.8 to 3.4) | 2.2 (1.1 to 3.2) | 2.7 (1.8 to 3.8) | 2.5 (1.7 to 3.4) | 2.1 (1.2 to 3.1) | 2.1 (1.2 to 3.2) | 0.4 (0.2 to 0.6) | 0.7 (0.2 to 1.2) |
East and Southern Africa | 60.2 (50.4 to 72.2) | 14.1 (11.8 to 16.6) | 7.4 (5.8 to 9.4) | 3.6 (2.2 to 5.0) | 3.0 (2.0 to 4.1) | 2.4 (1.6 to 3.1) | 3.3 (2.6 to 4.2) | 3.6 (2.5 to 4.7) | 1.3 (0.8 to 1.8) | 1.1 (0.5 to 1.8) | 0.4 (0.3 to 0.6) |
South Asia | 4.9 (3.4 to 7.1) | 1.2 (0.8 to 1.8) | 0.7 (0.4 to 1.1) | 0.3 (0.2 to 0.7) | 0.9 (0.5 to 1.3) | 0.2 (0.0 to 0.4) | 0.1 (0.0 to 0.1) | 0.1 (0.0 to 0.1) | 0.1 (0.0 to 0.2) | 0.2 (0.0 to 0.3) | 0.1 (0.0 to 0.1) |
Southeast Asia and Oceania | 14.3 (11.5 to 17.8) | 4.5 (3.6 to 5.7) | 0.9 (0.7 to 1.2) | 1.5 (1.1 to 1.8) | 0.8 (0.5 to 1.1) | 0.3 (0.2 to 0.4) | 0.2 (0.1 to 0.2) | 0.0 (0.0 to 0.1) | 0.3 (0.2 to 0.4) | 0.4 (0.2 to 0.5) | 0.1 (0.0 to 0.1) |
East Asia | 6.2 (4.2 to 9.1) | 1.7 (1.1 to 2.5) | 0.0 (0.0 to 0.0) | 0.8 (0.5 to 1.2) | 0.1 (0.0 to 0.2) | 0.1 (0.1 to 0.1) | 0.0 (0.0 to 0.0) | 0.0 (0.0 to 0.0) | 0.1 (0.1 to 0.2) | 0.0 (0.0 to 0.1) | 0.1 (0.0 to 0.1) |
Deaths† | 88.5 (76.2 to 103.0) | 34.0 (27.1 to 42.2) | 9.6 (6.9 to 12.0) | 6.3 (4.7 to 7.8) | 4.9 (3.9 to 6.4) | 3.6 (2.6 to 4.9) | 3.3 (2.6 to 4.1) | 3.0 (2.0 to 3.9) | 2.9 (2.0 to 3.8) | 1.2 (0.4 to 1.8) | 1.0 (0.5 to 1.4) |
Central America | 33.0 (22.2 to 47.7) | 5.7 (3.7 to 8.5) | 6.9 (3.6 to 11.5) | 3.7 (1.3 to 6.0) | 3.9 (1.6 to 7.8) | 0.9 (0.3 to 1.6) | 0.9 (0.3 to 1.6) | 1.5 (0.6 to 2.6) | 0.6 (0.3 to 1.1) | 1.0 (0.0 to 1.9) | 0.2 (0.1 to 0.3) |
South America | 11.6 (7.6 to 17.1) | 2.1 (1.2 to 3.7) | 1.3 (0.8 to 1.9) | 0.6 (0.3 to 0.9) | 2.6 (1.7 to 3.8) | 0.5 (0.3 to 0.8) | 0.4 (0.2 to 0.8) | 0.2 (0.1 to 0.3) | 0.1 (0.0 to 0.1) | 0.4 (0.2 to 0.6) | 0.1 (0.0 to 0.1) |
Eastern Europe | 0.8 (0.6 to 1.1) | 0.3 (0.2 to 0.4) | 0.0 (0.0 to 0.0) | 0.0 (0.0 to 0.0) | 0.1 (0.0 to 0.1) | 0.0 (0.0 to 0.0) | 0.0 (0.0 to 0.0) | 0.0 (0.0 to 0.0) | 0.0 (0.0 to 0.0) | 0.0 (0.0 to 0.1) | 0.0 (0.0 to 0.0) |
Central and Western Asia | 16.8 (11.0 to 25.9) | 3.5 (2.1 to 5.7) | 2.1 (1.3 to 3.4) | 0.6 (0.2 to 1.0) | 1.6 (1.0 to 2.4) | 1.1 (0.7 to 1.8) | 0.7 (0.4 to 1.1) | 0.7 (0.4 to 1.1) | 0.5 (0.2 to 1.0) | 0.1 (0.0 to 0.1) | 0.0 (0.0 to 0.0) |
West Africa | 358.1 (280.0 to 459.2) | 182.0 (131.7 to 241.6) | 33.2 (14.3 to 45.7) | 12.1 (4.8 to 18.5) | 16.0 (11.5 to 21.4) | 17.3 (11.4 to 24.1) | 15.4 (10.4 to 21.0) | 14.7 (8.3 to 21.3) | 12.1 (5.8 to 18.4) | 1.1 (0.6 to 1.7) | 4.5 (0.6 to 7.6) |
East and Southern Africa | 161.2 (128.3 to 210.4) | 34.8 (27.6 to 43.8) | 21.9 (16.3 to 30.4) | 7.7 (4.5 to 10.9) | 9.4 (4.9 to 13.9) | 6.1 (3.7 to 8.7) | 9.1 (6.8 to 12.4) | 3.9 (2.4 to 6.0) | 9.4 (6.1 to 13.3) | 3.2 (1.4 to 5.6) | 0.8 (0.4 to 1.2) |
South Asia | 52.8 (39.5 to 69.0) | 13.1 (9.7 to 17.5) | 7.0 (4.4 to 10.7) | 9.5 (5.9 to 12.8) | 3.5 (2.0 to 7.3) | 1.6 (0.4 to 3.9) | 0.8 (0.4 to 1.3) | 1.4 (0.3 to 2.3) | 1.0 (0.5 to 1.4) | 1.7 (0.0 to 3.0) | 0.8 (0.5 to 1.1) |
Southeast Asia and Oceania | 38.8 (30.3 to 49.0) | 13.3 (10.1 to 17.3) | 3.1 (2.2 to 4.2) | 2.5 (1.4 to 3.6) | 2.9 (2.1 to 3.7) | 0.6 (0.4 to 0.8) | 0.4 (0.3 to 0.6) | 1.0 (0.6 to 1.4) | 0.1 (0.1 to 0.2) | 1.0 (0.4 to 1.6) | 0.2 (0.1 to 0.4) |
East Asia | 2.3 (1.9 to 2.8) | 0.6 (0.5 to 0.8) | 0.0 (0.0 to 0.0) | 0.1 (0.0 to 0.1) | 0.3 (0.2 to 0.4) | 0.0 (0.0 to 0.0) | 0.0 (0.0 to 0.0) | 0.0 (0.0 to 0.0) | 0.0 (0.0 to 0.0) | 0.0 (0.0 to 0.0) | 0.0 (0.0 to 0.0) |
*Per 1000 child-years.
†Per 100 000 child-years.
ETEC, enterotoxigenic E. coli.