Estimated number of active TB cases detected and cost per DALY averted for HCD-informed TB contact investigation in Uganda
| Design | Bound | Active TB prevalence (cases/100 people) | Incremental contacts reached | Incremental cases detected | Incremental cost of HCD | Cost per case detected | DALYs averted per case detected | Cost per DALY averted |
| HCD as ‘disruptive’: no activity without HCD | Low | 2.2 | 720 | 15.8 | US$356 000 + US$0.41/contact | US$24 900 | 0.345 | US$72 100 |
| Mid | 3.1 | 22.3 | US$17 700 | US$51 200 | ||||
| High | 4.4 | 31.7 | US$12 400 | US$36 100 | ||||
| HCD as ‘incremental’: 40% efficiency without HCD | Low | 2.2 | 432 | 9.5 | US$356 000 + US$0.41/contact | US$41 500 | 0.345 | US$120 200 |
| Mid | 3.1 | 13.4 | US$29 400 | US$85 300 | ||||
| High | 4.4 | 19.0 | US$20 700 | US$60 100 |
DALY, disability-adjusted life year; HCD, human-centred design; TB, tuberculosis.