Crude OR (95% CI) | P value | Adjusted* OR (95% CI) | P value | |
Typhoid comes from mosquitoes | ||||
Intention-to-treat (n=583)† | ||||
Group A | 0.31 (0.20 to 0.48) | 0.000 | 0.29 (0.18 to 0.47) | 0.000 |
Group B | 0.50 (0.33 to 0.77) | 0.002 | 0.61 (0.39 to 0.95) | 0.029 |
Control | Reference | – | Reference | – |
Per-protocol (n=210) | ||||
Group A | 0.07 (0.02 to 0.19) | 0.000 | 0.06 (0.02 to 0.20) | 0.000 |
Group B | 0.31 (0.14 to 0.70) | 0.005 | 0.35 (0.15 to 0.84) | 0.019 |
Control | Reference | – | Reference | – |
As-treated (n=419) | ||||
Group A | 0.15 (0.08 to 0.27) | 0.000 | 0.13 (0.07 to 0.25) | 0.000 |
Group B | 0.33 (0.19 to 0.57) | 0.000 | 0.38 (0.21 to 0.68) | 0.001 |
Control | Reference | – | Reference | – |
Typhoid and malaria co-occur | ||||
Intention-to-treat (n=618)† | ||||
Group A | 0.32 (0.21 to 0.48) | 0.000 | 0.29 (0.19 to 0.45) | 0.000 |
Group B | 0.49 (0.33 to 0.73) | 0.000 | 0.55 (0.36 to 0.83) | 0.004 |
Control | Reference | – | Reference | – |
Per-protocol (n=220) | ||||
Group A | 0.07 (0.03 to 0.18) | 0.000 | 0.06 (0.02 to 0.15) | 0.000 |
Group B | 0.16 (0.07 to 0.36) | 0.000 | 0.15 (0.06 to 0.36) | 0.000 |
Control | Reference | – | Reference | – |
As-treated (n=434) | ||||
Group A | 0.13 (0.08 to 0.23) | 0.000 | 0.12 (0.07 to 0.21) | 0.000 |
Group B | 0.25 (0.15 to 0.42) | 0.000 | 0.27 (0.16 to 0.47) | 0.000 |
Control | Reference | – | Reference | – |
*Adjusted for sex, education, religion, income and age.
†Complete case analysis. Participants who responded ‘Don’t Know’ or ‘No Response’ in either baseline or endline were excluded. We analysed the impact of intervention assignment on endline non-response (see online supplemental table S9).