Table 2

Summary of studies that integrated mass drug administration

Study authorDiseasesWho distributed the drugsWho managed the programmeOutcome
Lemos et al28Schistosomiasis
STH
Malaria
Anaemia		Centro de Investigação em Saúde de Angola lab workersGovernment and researchersAll anaemia cases were associated with schistosomiasis −13.5% reduction in schistosomiasis infections with no significant changes in anaemia
Lemoine et al51LF
STH		Community drug distributors,ENVISION project100% coverage from as low as 30%
Njenga et al29Hookworm (STH)
Urogenital Schistosomiasis		Trained schoolteachersAuthorsDid not change both the overall prevalence and intensity of hookworm infection.
Ndayishimiye et al35STH
Schistosomiasis
Onchocerciasis
Trachoma		Community drug distributors and community health workersMinistry of HealthIncrease in total population covered from 3 209 521 in 2007 to 4 179 495 in 2010
Leslie et al65STH
Schistosomiasis
LF
Trachoma		–GovernmentIntegrated programme cost 21% less than vertical programmes
Evans et al30STH
Schistosomiasis
Onchocerciasis
LF		Community drug distributorsMinistry of Health98%–100% coverage, reduction in cost by 41.1%
Mwinzi et al50STH
Schistosomiasis		Community drug distributorsMinistry of Health52.3% to 91.9% coverage with a 69% prevalence reduction for hookworm
Mani et al67STH
LF		Community health workers–77% prevalence reduction compared 15% reduction for single drug (3× increase in control)
Bronzan et al27STH
Schistosomiasis		–Ministry of HealthDecrease in STH prevalence from 31.1% in 2009 to 11% in 2015
-Schisto 23.5% to 5%

  • ‘-’ means not clear.

  • LF, lymphatic filariasis; STH, soil transmitted helminths.