Summary of simulated cost and impact under different PPIA scenarios
| Site | PPIA scenario | DALYs averted (thousands) | Incremental spend (US$ millions) | US$ per DALY averted |
| Mumbai | Dx only | 29.4 (15–56.4) | 12.8 (6.64–26.2) | 441 (319–601) |
| Tx only | 24.4 (12.6–47.2) | 0.732 (0.153–1.16) | 30.5 (3.46–79.7) | |
| Both | 54.8 (30.3–95.5) | 12.4 (6.76–24.1) | 228 (159–320) | |
| Patna | Dx only | 2.87 (1.41–5.99) | 2.35 (1.25–4.78) | 803 (566–1120) |
| Tx only | 3.49 (1.82–6.81) | 0.255 (0.169–0.315) | 72.6 (29.6–157) | |
| Both | 4.27 (2.24–8.44) | 2.46 (1.34–4.77) | 564 (409–775) |
As described in the main text, ‘Tx only’ refers to a reduced PPIA that focuses efforts and spending in adherence support, while ‘Dx only’ focuses instead on quality of TB diagnosis. All estimates incorporate 3% annual discounting in both DALYs averted and incremental spend. Numbers are given under the assumption of 50% provider coverage. See also figure 3 for a visualisation of these results.
DALY, disability adjusted life years; PPIA, Public–Private Interface Agencies.