Birth outcomes by number of SP doses received during pregnancy
| Character | Overall (N=1926) | ≤1 dose (N=103) | 2 doses (N=369) | 3 doses (N=640) | ≥4 doses (N=814) | P value | |||||
| N | % | N | % | N | % | N | % | N | % | ||
| Pregnancy outcome | |||||||||||
| Delivered | 1899 | 98.6 | 97 | 94.2 | 362 | 98.1 | 634 | 99.1 | 806 | 99.0 | <0.001 |
| Aborted | 10 | 0.5 | 6 | 5.8 | 2 | 0.5 | 2 | 0.3 | 0 | 0.0 | |
| Stillbirth | 17 | 0.9 | 0 | 0.0 | 5 | 1.4 | 4 | 0.6 | 8 | 1.0 | |
| The following data are based on live births | |||||||||||
| Overall (N=1899) | ≤1 dose (N=97) | 2 doses (N=362) | 3 doses (N=632) | ≥4 doses (N=808) | |||||||
| Mean gestational age at delivery (±SD), weeks | 38.4 (2.4) N=1888 | 37.2 (4.7) N=95 | 38.2 (1.9) N=359 | 38.4 (1.8) N=630 | 38.6 (2.5) N=804 | <0.001 | |||||
| Preterm delivery<37weeksgestation | 226 | 12.0 | 21 | 22.1 | 58 | 16.2 | 70 | 11.1 | 77 | 9.6 | <0.001 |
| Mean birth weight (±SD)kg | 3.07 (0.48) N=1856 | 2.84 (0.58) N=95 | 2.99 (0.49) N=354 | 3.09 (0.47) N=615 | 3.11 (0.45) N=792 | <0.001 | |||||
| Low birth weight<2.5 kg | 140 | 7.5 | 17 | 17.9 | 36 | 10.2 | 40 | 6.5 | 47 | 5.9 | <0.001 |
| Mode of delivery | |||||||||||
| Spontaneous vaginal delivery | 1593 | 83.9 | 81 | 83.5 | 310 | 85.6 | 519 | 82.1 | 683 | 84.5 | 0.52 |
| Vacuum extraction | 18 | 1.0 | 1 | 1.0 | 1 | 0.3 | 6 | 1.0 | 10 | 1.2 | |
| Caesarean section | 288 | 15.2 | 15 | 15.5 | 51 | 14.1 | 107 | 16.9 | 115 | 14.2 | |
| Delivery complication | |||||||||||
| Post-partum haemorrhage | 26 | 1.37 | 5 | 5.15 | 8 | 2.21 | 7 | 1.1 | 6 | 0.7 | 0.001 |
| Eclampsia | 4 | 0.21 | 2 | 2.06 | 1 | 0.28 | 0 | 0.00 | 1 | 0.12 | 0.01 |
| Puerperal sepsis | 3 | 0.16 | 0 | 0.00 | 1 | 0.28 | 1 | 0.16 | 1 | 0.12 | 0.82 |
| Obstructed labour | 6 | 0.32 | 0 | 0.00 | 2 | 0.55 | 2 | 0.32 | 2 | 0.25 | 0.83 |
| Other | 21 | 1.11 | 1 | 1.03 | 5 | 1.38 | 7 | 1.11 | 8 | 0.99 | 0.91 |
| Congenital abnormalities | 9 | 0.47 | 0 | 0.00 | 1 | 0.28 | 6 | 0.95 | 2 | 0.25 | 0.28 |
| Jaundice | 3 | 0.16 | 0 | 0.00 | 1 | 0.28 | 2 | 0.32 | 0 | 0.0 | 0.34 |
| Hgb, cord blood, mean (±SD), g/L | 145 (2.38) N=1731 | 143 (2.15) N=90 | 145 (2.47) N=333 | 145 (2.38) N=580 | 146 (2.35) N=728 | 0.37 | |||||
| Neonatal anaemia (cord Hgb<125 g/L) | 266 | 15.37 | 19 | 21.11 | 55 | 16.52 | 96 | 16.55 | 96 | 13.19 | 0.12 |
P values based on χ2 test (categorical variables) and Kruskal-Wallis test (continuous variables).
Hgb, haemoglobin; ; SP, sulphadoxine-pyrimethamine.