Adjusted incidence rate ratios (IRRs) in 2015–2017 comparing clusters assigned to RACD versus rfMDA
| Study arm | N clusters | Incidence (cases per 1000 person-years) | Crude IRR | P value | Adjusted IRR* | P value |
| All cases | ||||||
| RACD | 22 | 1.97 (1.57 to 2.47) | 1 (Ref) | 0.99 | 1 (Ref) | 0.81 |
| rfMDA | 25 | 2.11 (1.73 to 2.59) | 1.01 (0.58 to 1.73) | 0.93 (0.54 to 1.62) | ||
| Local cases only | ||||||
| RACD | 22 | 0.97 (0.71 to 1.34) | 1 (Ref) | 0.85 | 1 (Ref) | 0.61 |
| rfMDA | 25 | 1.29 (1.00 to 1.67) | 1.06 (0.57 to 1.98) | 0.84 (0.42 to 1.66) | ||
95% CIs for incidence were estimated using the Wilson method. IRRs compared cluster-level incidence in the rfMDA arm to the RACD arm using an intention-to-treat approach and negative binomial models.
*Models adjusted for the following baseline covariates that were associated with the outcome: incidence of all cases from July 2014 to August 2015 (all cases model), incidence of local cases from July 2014–August 2015 (local cases only model).
RACD, reactive case detection; rfMDA, reactive focal mass drug administration