Clinical and pathological features of the cases with malaria as a contributor to death, in patients who died of other diseases
| Case | Age | Sex | Age group | Origin* | Malaria † seasonality | HIV | Haematocrit/ Haemoglobin | Parasitaemia/ rapid test | Cause of death | Evidence of malaria at autopsy | Detected by MIA |
| Patients with severe anaemia (malaria as a possible contributor to death) | |||||||||||
| 8 | 7 | M | Children 6—15 | Rural | High | HIV | 23/70 | Negative/ negative | Burkitt lymphoma | PCR parasitaemia (low) | Yes (PCR parasitaemia, low) |
| 9 | 10 | M | Children 6—15 | Urban | High | – | 9/30 | Negative/ negative | Sepsis due to Gram-negative bacteria | PCR parasitaemia (low) | Yes (PCR parasitaemia, low) |
| 11 | 10 | M | Children 6—15 | Rural | High | – | 9/20 | Negative/ negative | Sepsis due to Gram-negative bacteria | Haemozoin in liver, lung and spleen | No |
| 15 | 2 | M | Children u-5 | Urban | High | HIV | 21/70 | NA/negative | Sepsis (Gram-negative bacteria) | Haemozoin in liver and spleen | Yes (haemozoin in liver and spleen) |
| 16 | 27 | F | Maternal death | Urban | High | HIV | 18/60 | Negative/NA | Genital tract infection following abortion | Haemozoin in lung | No |
| 17 | 27 | F | Maternal death | Urban | High | HIV | 14/50 | Negative/NA | Liver failure | Haemozoin in spleen | No |
| 19 | 27 | F | Maternal death | Urban | High | – | 18/60 | NA/negative | Obstetric haemorrhage | Haemozoin in liver | Yes (haemozoin in liver) |
| Patients with mild to moderate anaemia or with no available data (malaria as associated condition) | |||||||||||
| 7 | 0 | F | Neonate | Urban | High | – | 41/140 | NA/NA | Neonatal sepsis, congenital malaria | PCR parasitaemia (107,167) | Yes (PCR parasitaemia, 107,167) |
| 10 | 4 | M | Children u-5 | Urban | Low | – | 28/90 | Negative/ negative | Encephalitis | Haemozoin in liver and spleen | Yes (haemozoin in liver and spleen) |
| 14 | 13 | M | Children 6—15 | Urban | High | – | 41/130 | NA/negative | Sepsis (Streptococcus pneumoniae) | Haemozoin in liver and spleen | Yes (haemozoin in liver and spleen) |
| 12 | 6 | F | Children 6—15 | Urban | High | – | 33/110 | Negative/NA | Encephalitis | Haemozoin in liver and spleen | Yes (haemozoin in liver and spleen) |
| 13 | 4 | M | Children u-5 | Rural | Low | – | 30/100 | NA/NA | Burkitt lymphoma | Haemozoin in liver | Yes (haemozoin in liver) |
| 18 | 32 | F | Maternal death | Urban | High | – | NA | NA/NA | Obstetric haemorrhage | Haemozoin in liver | Yes (haemozoin in liver) |
*Urban usually corresponds to Maputo city, whereby malaria incidence is generally low. Rural implies other areas where malaria incidence tends to be higher.
†Seasonality for malaria is high during the rainy season (October to May), and low during the dry season (June to September).
F, female; M, male; MIA, minimally invasive autopsy; NA, not available; u-5, under 5 years of age.