Table 4

Demographic characteristics, clinical features, laboratory data and final diagnosis (gold standard) of the patients with clinical diagnosis of malaria or diagnosed of malaria by verbal autopsy

CaseAgeSexAge groupOriginMalaria * incidencePrevious conditionsFeverHaematocrit/
Haemoglobin
Parasitaemia/ rapid testCause of death
Clinical diagnosis of malaria
323FMaternal deathUrbanHighHIVYes22/80Positive/positiveCerebral malaria
428FMaternal deathUrbanHighHIVYes20/70Negative/positiveCerebral malaria
620FMaternal deathUrbanHighNo24/70NA/NACerebral malaria
1110MChildren 6–15RuralHighYes9/20Negative/negativeGram-negative sepsis‡
126FChildren 6–15UrbanHighYes33/110Negative/NAEncephalitis‡
2034FMaternal deathUrbanHighNo29/100NA/NAStreptococcal sepsis
2117MAdultUrbanHighYes34/120Negative/NAPneumococcal meningitis
2240FAdultUrbanHighHIVYes22/80Negative/NACytomegalovirus pneumonitis
Clinical diagnosis of malaria and verbal autopsy classified as malaria
12MChildren u-5UrbanHighNANA/NAPositive/NASevere malaria
2333FAdultUrbanHighYesNA/NANA/NAGastroenteritis
2425MAdultUrbanHighHIVYes44/160Negative/positiveDisseminated cryptococcosis
2550MAdultUrbanHighHIVYesNA/NANA/NAPneumococcal meningitis
Verbal autopsy classified as malaria
23MChildren u-5UrbanHighYesNA/NANA/NACerebral malaria
1627FMaternal deathUrbanHighHIVYes18/60Negative/NAPuerperal sepsis‡
1927FMaternal deathUrbanHighNo18/60NA/negativeHaemorrhage postabortion‡
260MChildren u-5UrbanHighYes18/60Negative/negativePneumococcal meningitis
2728FMaternal deathUrbanHighHIVNo14/50Negative/negativeLiver failure
2816FMaternal deathUrbanHighYes10/30NA/NALiver failure
2928FAdultUrbanHighYes12/40Negative/negativeBacterial sepsis
3037MAdultRuralHighHIVYesNA/NANA/NABacterial sepsis
  • *Urban usually corresponds to Maputo city, whereby malaria incidence is generally low. Rural implies other areas where malaria incidence tends to be higher.

  • †Seasonality for malaria is high during the rainy season (October to May), and low during the dry season (June to September).

  • ‡Histological evidence of past malaria (haemozoin accumulation in liver and spleen) identified in the autopsy.

  • F, female; M, male; NA, not available; u-5, under 5 years of age.