Baseline characteristics of study participants with and without social isolation
| Characteristic | No social isolation (n=1 05 772) | Social isolation (n=12 992) | P value Univariate analysis |
| Age, year | 50.1±9.8 | 52.2±10.2 | <0.0001 |
| Women (%) | 59 567 (56.3) | 9402 (72.4) | <0.0001 |
| Hypertension (%) | 22 682 (21.5) | 3372 (26.0) | <0.0001 |
| Diabetes mellitus (%) | 10 066 (9.5) | 1357 (10.5) | 0.001 |
| Coronary artery disease (%) | 3115 (3.0) | 443 (3.4) | 0.003 |
| Stroke (%) | 1396 (1.3) | 271 (2.1) | <0.0001 |
| Cancer (%) | 1646 (1.6) | 255 (2.0) | 0.001 |
| COPD (%) | 845 (0.9) | 159 (1.2) | 0.001 |
| Depression (%) | 15 570 (14.8) | 2670 (20.6) | <0.0001 |
COPD, chronic obstructive pulmonary disease.