Controls n=2316 | Cases n=568 | P value | |
Gender, N (%) | 0.63 | ||
Female | 640 (28%) | 154 (27%) | |
Male | 1656 (72%) | 410 (72%) | |
Other | 1 (0%) | 1 (0%) | |
Prefer not to say | 19 (1%) | 3 (1%) | |
Age (mean±SD) | 48±10 | 47±10 | 0.11 |
Significant, close exposure to COVID-19 | 100% | 100% | . |
Experienced symptoms of COVID-19 | 0 (0%) | 514 (90%) | . |
Number of days of symptoms | 0 | 11±13 | . |
Country | <0.001 | ||
France | 208 (9%) | 48 (8%) | |
Germany | 233 (10%) | 46 (8%) | |
Italy | 359 (16%) | 74 (13%) | |
Spain | 382 (16%) | 146 (26%) | |
UK | 233 (10%) | 94 (17%) | |
USA | 901 (39%) | 160 (28%) | |
Race/ethnicity | 0.46 | ||
White | 1792 (77%) | 426 (75%) | |
Any mixed/multiple ethnic background | 121 (5%) | 41 (7%) | |
Asian | 271 (12%) | 65 (11%) | |
African | 36 (2%) | 12 (2%) | |
Other | 29 (1%) | 7 (1%) | |
Prefer not to say | 67 (3%) | 17 (3%) | |
Smoking | 0.80 | ||
Current smoker | 110 (5%) | 24 (4%) | |
Former smoker | 341 (15%) | 86 (15%) | |
Never smoked | 1865 (81%) | 458 (81%) | |
Medical doctor | 2187 (94%) | 548 (96%) | 0.048 |
Nurse/nurse practitioner/physician assistant | 129 (6%) | 20 (4%) | |
Physician specialty | 0.10 | ||
Other | 10 (0%) | 2 (0%) | |
Allergy and immunology | 25 (1%) | 4 (1%) | |
Cardiology | 227 (10%) | 54 (10%) | |
Critical care | 230 (10%) | 52 (9%) | |
Emergency medicine | 512 (22%) | 91 (16%) | |
Endocrinology, diabetes, and metabolism | 74 (3%) | 24 (4%) | |
Gastroenterology | 77 (3%) | 17 (3%) | |
Haematology | 85 (4%) | 27 (5%) | |
Infectious disease | 82 (4%) | 18 (3%) | |
Internal medicine | 322 (14%) | 111 (20%) | |
Nephrology | 38 (2%) | 15 (3%) | |
Neurology | 82 (4%) | 25 (5%) | |
Pulmonology | 354 (15%) | 76 (13%) | |
Rheumatology | 69 (3%) | 32 (6%) | |
Nurse/NP/PA practice setting | 0.36 | ||
Emergency room | 22 (17%) | 2 (10%) | |
Intensive care unit (ICU) | 45 (35%) | 5 (25%) | |
Other hospital-based department | 62 (48%) | 13 (65%) | |
Medical conditions | |||
Pre-diabetes | 38 (1.6%) | 16 (2.8%) | 0.06 |
Diabetes | 70 (3.0%) | 26 (4.6%) | 0.06 |
High cholesterol | 320 (13.8%) | 76 (13.4%) | 0.79 |
Cancer | 326 (14.1%) | 78 (13.7%) | 0.83 |
Coronary heart disease | 59 (2.5%) | 11 (1.9%) | 0.4 |
Heart failure | 31 (1.3%) | 13 (2.3%) | 0.1 |
Prior lung disease | 8 (0.3%) | 2 (0.4%) | 0.98 |
Prior lung infection | 9 (0.4%) | 4 (0.7%) | 0.31 |
Asthma | 34 (1.5%) | 6 (1.1%) | 0.45 |
Overweight | 218 (9.4%) | 69 (12.1%) | 0.05 |
Autoimmune disease | 307 (13.3%) | 81 (14.3%) | 0.53 |
COVID-19 PCR or antibody test | <0.001 | ||
No—I did not a get a test | 695 (30%) | 53 (9%) | |
No—I did not have access to the test | 69 (3%) | 32 (6%) | |
Yes—I tested negative | 1552 (67%) | 185 (33%) | |
Yes—I tested positive | 0 (0%) | 298 (52%) | |
Test for influenza or other respiratory viruses | <0.001 | ||
No—I did not a get a test | 1876 (81%) | 418 (74%) | |
No—I did not have access to the test | 205 (9%) | 50 (9%) | |
Yes—I tested negative | 225 (10%) | 79 (14%) | |
Yes—I tested positive | 10 (0%) | 21 (4%) |
Cases are defined as self-reported COVID-19 like illness or a positive COVID-19 test in the absence of symptoms.
NP, nurse practitioner; PA, physician assistant.