Table 2

Relationships between participant characteristics and latent tuberculosis infection (LTBI) among individuals in the UK

CharacteristicsLTBI
Negative N (%)Positive N (%)Crude OR (95% CI)P valueAdjusted OR (95% CI)P value
Area deprivation
 Most deprived3527 (71.8)1387 (28.2)11
 Moderately deprived2436 (72.6)919 (27.4)0.96 (0.87 to 1.06)0.92 (0.81 to 1.03)
 Least deprived380 (78.8)102 (21.2)0.68 (0.54 to 0.86)0.0030.68 (0.51 to 0.90)0.013
Ever smoked
 No5356 (72.5)2036 (27.5)11
 Yes1246 (71.8)489 (28.2)1.03 (0.92 to 1.16)0.5910.99 (0.85 to 1.15)0.893
History of substance misuse
 No6459 (72.2)2482 (27.8)11
 Yes148 (76.7)45 (23.3)0.79 (0.56 to 1.11)0.1730.83 (0.55 to 1.25)0.360
Ever been homeless
 No6498 (72.5)2462 (27.5)11
 Yes113 (63.1)66 (36.9)1.54 (1.13 to 2.10)0.0061.50 (1.02 to 2.21)0.043
Ever been in prison
 No6524 (72.4)2484 (27.6)11
 Yes83 (65.9)43 (34.1)1.36 (0.94 to 1.97)0.1041.35 (0.85 to 2.15)0.210
Gender
 Male3152 (69.2)1406 (30.9)11
 Female3443 (75.5)1115 (24.5)0.73 (0.66 to 0.80)<0.0010.69 (0.62 to 0.77)<0.001
Age (years)1.01 (1.00 to 1.01)<0.0011.01 (1.00 to 1.01)<0.001
Place of birth
 Non-UK5391 (70.3)2276 (29.7)11
 UK1223 (83.3)246 (16.8)0.41 (0.41 to 0.55)<0.0010.41 (0.34 to 0.49)<0.001
Ethnicity
 Asian3895 (73.1)1437 (27.0)11
 White879 (79.0)234 (21.0)0.72 (0.62 to 0.84)0.87 (0.71 to 1.07)
 Black870 (66.4)440 (33.6)1.37 (1.20 to 1.56)1.29 (1.10 to 1.52)
 Mixed/other835 (70.6)348 (29.4)1.13 (0.98 to 1.30)<0.0011.11 (0.93 to 1.31)0.002
HIV status
 Negative6125 (72.2)2362 (27.8)11
 Positive38 (73.1)14 (26.9)0.96 (0.52 to 1.77)0.8840.80 (0.40 to 1.62)0.535
BCG vaccination
 No1025 (72.4)390 (27.6)11
 Yes4620 (72.8)1726 (27.2)0.98 (0.86 to 1.12)0.7810.89 (0.78 to 1.03)0.128
Recent TB contact
 No3333 (74.5)1141 (25.5)11
 Yes3231 (70.3)1374 (29.8)1.24 (1.13 to 1.36)<0.0011.44 (1.27 to 1.63)<0.001
  • Percentages may not add to 100 due to rounding.

  • A total of 6488 individuals included in the multivariable analysis.

  • Multivariable logistic regression model was fitted to include LTBI, all of the social risk factors and all variables associated with LTBI or one of the social risk factors.