Table 2

Effectiveness of sulfadoxine-pyrimethamine for intermittent preventive treatment in pregnancy (IPTp) and in infancy (IPTi)

IPTpIPTi
2000200520102015202020002005201020152020
Angola0.950.940.930.900.861.001.001.001.001.00
Benin0.950.940.930.900.861.001.001.001.001.00
Burkina Faso0.990.990.990.990.981.001.001.001.001.00
Cameroon0.950.940.930.900.861.001.001.001.001.00
Congo0.950.940.930.900.801.001.000.990.510.02
Democratic Republic of the Congo0.950.940.930.900.860.920.920.910.910.91
Equatorial Guinea0.000.000.000.991.001.001.001.000.990.89
Ethiopia0.610.560.530.510.540.030.030.030.040.05
Gabon1.001.001.001.001.001.001.001.001.001.00
Ghana0.990.990.990.990.981.001.001.001.001.00
Kenya1.000.900.790.960.800.240.010.000.070.88
Malawi0.780.380.030.000.000.020.000.000.000.00
Mali0.990.990.990.990.981.001.001.001.001.00
Mozambique1.001.000.980.840.760.920.740.210.030.03
Nigeria0.670.670.670.660.650.900.981.001.001.00
Senegal1.001.001.001.001.001.001.001.001.001.00
South AfricaNANANANANA0.950.950.940.930.92
Sudan0.920.790.730.710.730.960.040.060.951.00
Tanzania0.990.950.790.750.800.930.310.040.050.26
The Gambia0.990.990.990.990.981.001.001.001.001.00
Uganda0.250.210.170.180.220.030.010.000.000.01
Zambia0.700.690.680.660.620.480.470.470.470.47
  • The values in each country-year are posterior probability reflecting the amount of evidence that each intervention is effective under the current WHO frameworks. For IPTp, the WHO thresholds for withdrawal of policy are pfdhps540E >95% and pfdhps581G >10%. For IPTi, the WHO threshold for withdrawal of policy is pfdhps540E >50%. For each intervention, we consider the drug effective in those country-years whose posterior probability >95%. For detailed year-specific policy effectiveness, see online supplemental file 3.6. For South Africa, the data are not sufficient to generate evidence on drug effectiveness for IPTp.

  • NA, not available.