Mean (SD) GHSI scores for countries receiving US GHSA investment versus GHSI scores of matched controls not receiving US GHSA investment
| GHSI total | Prevention | Detection and reporting | Rapid response | Health system | Compliance with international norms | Risk environment | |
| US GHSA recipient countries | 40.6 (10.3) | 34.9 (13.5) | 46.7 (15.7) | 39.6 (13.2) | 24.2 (14.7) | 55.0 (9.4) | 44.0 (10.9) |
| Non-recipient countries | 34.6 (8.3) | 29.1 (10.5) | 36.8 (16.4) | 34.9 (10.1) | 20.4 (11.1) | 45.8 (8.5) | 42.9 (11.4) |
| Difference in GHSI score | +6.0 | +5.8 | +9.9 | +4.7 | +3.8 | +9.3 | +1.1 |
| P value | 0.0011 | 0.0252 | 0.0062 | 0.0477 | 0.1125 | 0.0001 | 0.5207 |
Countries were matched within WHO region by next closest GDP per capita, with small island nations of <1 million population excluded.
GDP, gross domestic product; GHSA, Global Health Security Agenda; GHSI, Global Health Security Index.;