Table 2

Associations between maternally-reported danger signs, birth weight, gestational age and neonatal mortality

Infants
(n=14 944)
Deaths
(n=192)
Mortality rate*Univariate
OR (95% CI)
Multivariable†
OR (95% CI)
Individual predictors
 Lethargy‡495810420.982.16 (1.69 to 2.76)1.51 (1.15 to 1.98)
 Cyanosis‡317928.392.40 (1.36 to 4.23)1.10 (0.54 to 2.24)
 Non-cephalic presentation‡3091238.833.47 (2.10 to 5.73)2.59 (1.49 to 4.48)
 Trouble suckling‡12255444.085.07 (3.84 to 6.69)3.47 (2.57 to 4.70)
 Birth weight‡
  <2.5 kg631714022.164.05 (3.05 to 5.38)2.67 (1.95 to 3.64)
  <2.0 kg§11729177.6512.1 (9.4 to 15.5)6.46 (4.79 to 8.73)
  <1.5 kg§11036327.2750.8 (35.3 to 73.0)16.7 (10.8 to 25.7)
 Gestational age‡
  <37 weeks279010035.844.87 (3.78 to 6.28)3.58 (2.72 to 4.71)
Number of reported danger signs
 None8908667.41REFREF
 One48397014.471.85 (1.38 to 2.47)1.64 (1.21 to 2.21)
 Two8203745.126.23 (4.39 to 8.85)4.33 (2.97 to 6.32)
 Three759120.016.2 (8.36 to 31.3)8.86 (4.35 to 18.1)
 Four30NANANA
  • *Mortality rate expressed in deaths per 1000 live births.

  • †Multivariable models for individual predictors include lethargy, cyanosis, malpresentation, poor suckling, birth weight < 2.5 g and gestational age <37 weeks.

  • ‡Missing data on lethargy for 93 infants (0 of which died), cyanosis for 48 infants (of which 0 died), non-cephalic presentation for 16 infants (in which 0 died), trouble suckling for 153 infants (of which 10 died), birth weight for 36 infants (3 of which died) and gestational age for 638 infants (7 of whom died).

  • §Multivariable model includes birth weight <1.5 kg or <2.0 kg in lieu of birth weight <2.5 kg.