Table 2

Typhoid target product profile characteristics: scope of the test

CharacteristicMinimal requirementOptimal requirementReferences
GoalPoint-of-care test to improve patient management through diagnosis and treatment of infection with acute Salmonella enterica serovars Typhi or ParatyphiCombine with diagnostics for malaria and other causes of acute febrile illness as part of a treatment algorithm8 41
Target populationAll individuals with undifferentiated acute fever15 27 30
Target userLaboratory technicianHealthcare worker7
Target level of health system*District hospital with basic laboratory facilitiesPrimary health posts and centres6 31
  • *Consensus not reached among survey respondents.