Table 4

Univariate associations for mortality among all children admitted to the study hospitals with pneumonia

CharacteristicNumber of deaths/number of patientsMortalityOR (95% CI)P value
Age 10–14 years51/36314.05%2.38 (1.66 to 3.42)<0.001
Age 5–9 years94/14626.43%
Male75/10197.36%0.83 (0.59 to 1.16)0.318
Female70/8008.75%
High malaria transmission region85/84610.05%1.71 (1.21 to 2.41)0.003
Low malaria transmission region60/9796.13%
Referred48/32214.91%2.63 (1.78, 3.86)<0.001
Not referred74/11836.26%
Readmitted13/2794.66%0.55 (0.31 to 1.00)0.063
Not readmitted101/12438.13%
Temperature ≥38.0°C47/6677.05%0.94 (0.64 to 1.38)0.83
Temperature <38.0°C72/9667.45%
Respiratory rate >3094/11268.35%1.92 (1.13 to 3.27)0.019
Respiratory rate ≤3017/3764.52%
Central cyanosis5/2520%3.20 (1.18 to 8.67)0.033
No central cyanosis126/17397.25%
Grunting35/27012.96%2.15 (1.42 to 3.24)<0.001
No grunting95/14656.48%
Acidotic breathing10/7014.29%2.21 (1.10 to 4.43)0.04
No acidotic breathing116/16557.01%
Reduced consciousness37/12828.91%6.65 (4.30 to 10.27)<0.001
Alert93/16135.77%
Cannot eat or drink47/29615.88%3.42 (2.31 to 5.07)<0.001
Can eat and drink72/13785.22%
Stridor7/5812.07%1.75 (0.78 to 3.93)0.268
No stridor119/16337.29%
Difficulty breathing82/9009.11%1.47 (1.03 to 2.10)0.04
No difficulty breathing55/8626.38%
Wheeze8/2233.59%0.43 (0.20 to 0.88)0.026
No wheeze122/15168.05%
Crackles59/6139.62%1.59 (1.11 to 2.29)0.014
No crackles70/11186.26%
Severe pallor34/11330.09%9.57 (5.94 to 15.41)<0.001
Mild/Moderate pallor40/22417.86%4.83 (3.15 to 7.41)<0.001
No pallor61/14174.30%1
Chest wall indrawing65/7119.14%1.45 (1.01 to 2.07)0.05
No chest wall indrawing67/10316.50%
Convulsions37/25214.68%2.48 (1.65 to 3.72)<0.001
No convulsions97/14956.49%
Oxygen saturations <90%25/17913.97%2.76 (1.61 to 4.76)<0.001
Oxygen saturations ≥90%35/6315.55%
Mid-upper arm circumference <115 mm8/4717.02%3.81 (1.66 to 8.77)0.002
Mid-upper arm circumference <115 mm35/6855.11%
Severe pneumonia77/58313.21%2.86 (2.01 to 4.07)<0.001
Non-severe pneumonia61/12095.05%
HIV positive33/18118.23%3.05 (2.00 to 4.66)<0.001
Not HIV positive112/16446.81%
Malaria diagnosed48/5428.86%1.19 (0.83 to 1.71)0.401
No malaria diagnosed97/12837.56%
Severe malnutrition30/17716.95%2.72 (1.76 to 4.21)<0.001
No severe malnutrition115/16486.98%
Sickle cell disease7/5313.21%1.80 (0.80 to 4.07)0.238
No sickle cell disease138/17727.79%
Asthma2/1951.03%0.11 (0.03 to 0.44)<0.001
No asthma143/16308.77%
Cardiac disease5/2520%2.96 (1.10 to 8.02)0.043
No cardiac disease140/18007.78%
Renal disease2/1513.33%1.79 (0.40 to 8.03)0.337
No renal disease143/18107.90%
Diabetes1/425%3.88 (0.40 to 37.56)0.282
No diabetes144/18217.91%
Chronic neurological disorder7/1345.22%0.62 (0.28 to 1.35)0.296
No chronic neurological disorder138/16918.16%
Sepsis3/933.33%5.89 (1.46 to 23.82)0.029
No sepsis142/18167.82%
Diarrhoea with dehydration14/10413.46%1.89 (1.05 to 3.41)0.051
No diarrhoea with dehydration131/17217.61%
Acute neurological disorder53/19427.32%6.29 (4.30 to 9.19)<0.001
No acute neurological disorder92/16315.64%