Table 1

Priority topics identified through priority setting processes across the three hubs

CAN hubPriority topic/QuestionCurrent status
West AfricanCommunity-based vs facility-based directly observed intermittent preventive therapy in pregnancy for preventing malariaRegistered with PROSPERO
Booster dose of Bacille Calmette-Guerin vaccine for preventing tuberculosis in LMICsRegistered with PROSPERO
Mass deworming or targeted deworming for preventing or treating anaemia or improving nutritional status and cognition in children –
Cognitive behavioural therapy plus pharmacological therapy versus pharmacological therapy for vaso-occlusive pain in children with sickle cell –
Early screening for preventing breast cancer –
Public health education for preventing breast cancer –
Hand hygiene for preventing infections in neonatesRegistered with Cochrane Neonatal Review Group
Self-breast examination for preventing cancer –
FrancophoneEffects of structured antiretroviral therapy treatment interruptions in chronic suppressed HIV-infected African adults –
Pattern of cardiovascular disease in African patients with chronic renal failure –
Cost-effectiveness of Procalcitonin in the follow-up of bacterial infections –
Prevalent pulmonary embolism, mortality rate, disease determinants and predictors of mortality following non-cardiac surgery in sub-Saharan Africans –
Southern-EasternIn patients with ESRD, what are the effects of different frequency (eg, thrice vs twice per week dialysis) or duration of dialysis (eg, 3 hours vs 4.5 hours) on quality of life and cost-effectiveness outcomes?Title registered with Cochrane Renal and Transplant Review as ‘Less intensive vs conventional haemodialysis for people with end-stage kidney disease’
Among adult patients on haemodialysis with intradialytic hypotension, what are the effects of changing dialysate sodium on reducing intradialytic hypotension? –
  • CAN, Cochrane Africa Network; ESRD, end stage renal disease; LMICs, low-income and middle-income countries.