Table 1

Paired government procurement prices, originator and biosimilar insulins, 1000 IU in US dollars

SurveyHuman insulin, strength, presentationOriginator(s)Biosimilar(s)Difference biosimilar to originator
PakistanRegular, isophane and mixed 30/70, 100 IU/mL vial$2.38 N$2.00 G16% ↓
Kazan, RussiaRegular 100 IU/mL vial$6.07 N$6.65 P10% ↑
Shaanxi, ChinaMixed 30/70 40 IU/mL vial$21.26 N$18.90 D11% ↓
Isophane 100 IU/mL cartridge$28.35 N$24.23 U; $25.21 D11%–14% ↓
Mixed 30/70 100 IU/mL cartridge$28.35 N$25.21 U; $25.21 D11% ↓
Mixed 50/50 100 IU/mL cartridge$28.35 N$25.05 U; $26.96 D5%–12%↓
Hubei, ChinaRegular 40 IU/mL vial$20.70 N$17.71 D14% ↓
Isophane 40 IU/mL vial$20.76 N$17.71 D14% ↓
Mixed 30/70 40 IU/mL vial$21.39 N$17.94 D16% ↓
Regular 100 IU/mL cartridge$26.51 L; $26.53 N$23.18 Li; $23.62 D; $27.41 Bt3% ↑–13% ↓
Isophane 100 IU/mL cartridge$26.20 L; $27.47 N$23.35 Li; $24.24 D; $28.11 Bt7% ↑–15% ↓
Mixed 30/70 100 IU/mL cartridge$26.44 L; $26.66 N$22.56 Li; $23.80 D; $27.84 Bt5% ↑–15% ↓
Mixed 50/50 100 IU/mL cartridge$27.78 N$22.09 Li; $26.23 D6%–20% ↓
  • Originator companies: L, Lilly; N, Novo Nordisk.

  • Biosimilar companies: Bt, Bioton; D, Tonghua Dongbao; G, Getz; Li, Lianbang; P, Pharmstandard; U, United.