Impact of Programme for Improving Mental Health Care mental healthcare plan on individual level outcomes in the depression and AUD cohort
| Comparison group | Treatment group | Unadjusted β or RR (95% CI) | Adjusted β or RR (95% CI) | |||||
| N | Mean (SD) or N (%) | Adjusted mean change (95% CI) from BL | N | Mean (SD) or N (%) | Adjusted mean change (95% CI) from BL | |||
| Depression cohort | ||||||||
| PHQ-9 score | ||||||||
| Baseline | 149 | 13.4 (2.63) | – | 238 | 14.5 (3.22) | – | ||
| Midline | 134 | 9.6 (4.18) | −3.18 (−4.04 to −2.31) | 201 | 7.5 (3.92) | −6.02 (−7.00 to −5.05) | −3.22 (−4.352 to −2.09) | −2.85 (−3.88 to −1.81)*** |
| Endline | 131 | 9.0 (3.98) | −3.69 (−4.59 to −2.79) | 191 | 7.3 (4.15) | −6.26 (−7.25 to −5.26) | −2.88 (−4.00 to −1.76) | −2.57 (−3.58 to −1.55)*** |
| WHODAS score | ||||||||
| Baseline | 144 | 30.7 (13.71) | – | 217 | 26.4 (15.14) | |||
| Midline | 135 | 26.8 (13.59) | −3.52 (−6.08 to −0.97) | 203 | 21.2 (11.22) | −4.07 (−5.89 to −2.25) | −0.69 (−4.44 to 3.06) | −0.55 (−3.50 to 2.41) |
| Endline | 130 | 26.9 (12.87) | −3.61 (−6.18 to −1.04) | 191 | 22.8 (11.93) | −2.82 (−4.61 to −1.04) | 0.90 (−2.92 to 4.73) | 0.79 (−2.22 to 3.80) |
| Response (PHQ-9) | ||||||||
| Midline | 134 | 36 (26.9) | – | 201 | 105 (52.2) | – | 1.94 (1.43 to 2.65) | 1.68 (1.22 to 2.30)** |
| Endline | 131 | 40 (30.5) | – | 191 | 109 (57.1) | – | 1.87 (1.40 to 2.49) | 1.56 (1.16 to 2.10)** |
| Early remission (PHQ-9) | 134 | 60 (44.8) | – | 201 | 141 (70.2) | – | 1.57 (1.27 to 1.93) | 1.50 (1.21 to 1.87)*** |
| Late remission (PHQ-9) | 73 | 31 (42.5) | – | 57 | 29 (50.9) | – | 1.20 (0.83 to 1.73) | 1.24 (0.84 to 1.84) |
| Recovery (PHQ-9) | 130 | 37 (28.5) | – | 189 | 106 (56.1) | – | 1.97 (1.46 to 2.66) | 1.82 (1.33 to 2.48)*** |
| AUD Cohort | ||||||||
| AUDIT Score | ||||||||
| Baseline | 147 | 14.3 (4.88) | – | 217 | 18.4 (7.76) | – | – | – |
| Endline | 104 | 10.4 (5.44) | −3.32 (−4.47 to −2.17) | 137 | 11.3 (7.48) | −6.03 (−7.21 to −4.85) | −3.23 (−5.14 to −1.33) | −2.71 (−4.29 to −1.13)** |
| WHDOAS score | ||||||||
| Baseline | 135 | 22.4 (11.73) | 204 | 19.4 (12.80) | ||||
| Midline | 128 | 21.7 (10.23) | −0.54 (−2.94 to 1.86) | 190 | 18.2 (10.64) | −0.66 (−2.20 to 0.89) | −0.33 (−3.64 to 2.98) | 0.12 (−2.97 to 2.74) |
| Endline | 118 | 22.2 (12.41) | −0.58 (−3.05 to 1.88) | 174 | 19.4 (10.21) | 0.56 (−1.08 to 2.20) | 1.26 (−2.17 to 4.70) | 1.14 (−1.82 to 4.10) |
| Late remission (AUDIT) | 104 | 25 (24.0) | – | 137 | 43 (31.4) | – | 1.31 (0.86 to 1.99) | 1.44 (0.95 to 2.20) |
*P<0.05; **p<0.01; ***p<0.001.
AUD, alcohol use disorder; AUDIT, Alcohol Use Disorder Identification Test;BL, Baseline;PHQ-9, Patient Health Questionnaire-9 item;RR, risk ratio; WHODAS, WHO Disability Assessment Schedule.