Table 3

Logistic regression to identify factors that influence the probability that the ICER is greater than the weighted median for ratios in the north-east quadrant for cost-per-QALY studies

Model 1: disease areaModel 2: full
VariableORSEP valueORSEP value
Disease area=oncology3.03***1.120.0033.22***1.270.003
Sponsor=industry0.660.380.466
Author=industry0.430.390.352
Study quality (subjective score)1.27*0.170.069
Constant0.70*0.150.0860.21**0.150.026
Observations208208
  • Variables were coded as follows: disease area oncology=1, disease area not oncology=0; study sponsor included industry=1, sponsor did not include industry=0; author list included industry=1, author list did not include industry=0; study quality=1–7 interval scale (half-points were possible).

  • ***p<0.01; **p<0.05; *p<0.10.

  • ICER, incremental cost-effectiveness ratio; OR, odds ratio; QALY, quality-adjusted life-year; SE, standard error.