Financial impact, HAT Tbg programmes across sub-Saharan African
| Control 2020 (Counterfactual) | Elimination I 2020 ~US$200 per DALY averted | Elimination II 2020 ~US$700 per DALY averted | Elimination III 2020 ~US$1500 per DALY averted | |||||||||
| Total (USD million) | 95% CI (USD million) | Total (USD million) | 95% CI (USD million) | Total (USD million) | 95% CI (USD million) | Total (USD million) | 95% CI (USD million) | |||||
| Total, gross-financial impact* | 630.6 | 630.3–631.0 | 410.9 | 410.7–411.1 | 988.0 | 987.6–988.5 | 1248.1 | 1247.2–1249.1 | ||||
| Total, net-financial impact† | NA | NA | −219.8 | −219.6 to −219.9 | 357.4 | 357.3–357.5 | 617.5 | 616.9–618.1 | ||||
| Country, income-level, gross-financial impact | ||||||||||||
| GNI | Cases in 2013‡ | Population at risk* (×103) | ||||||||||
| Sub-Saharan Africa* | 6228 | 54 958 | ||||||||||
| LIC | 1006 or less | 6105 | 45 325 | 546.97 | 546.65 to 547.28 | 353.05 | 352.77 to 333.14 | 765.29 | 764.92 to 765.34 | 998.19 | 997.45 to 999.04 | |
| LMIC | 1006–3995 | 33 | 4369 | 23.15 | 23.13 to 23.15 | 17.82 | 17.80 to 17.82 | 116.90 | 116.84 to 116.96 | 129.68 | 129.61 to 129.76 | |
| UMIC§ | 3996–12 235 | 89 | 5209 | 60.51 | 60.47 to 60.55 | 40.08 | 40.06 to 40.11 | 105.85 | 105.79 to 105.91 | 120.21 | 120.12 to 120.28 | |
| Country, gross-financial impact | ||||||||||||
| CAR | 330 | 59 | 555 | 6.94 | 6.93–6.94 | 4.5 | 4.45–4.46 | 8.66 | 8.66–8.66 | 11.00 | 10.99–11.01 | |
| DRC | 380 | 5647 | 38 032 | 454.66 | 454.40–454.93 | 293.6 | 293.4–293.7 | 641.1 | 640.8–641.4 | 835.1 | 834.5–835.8 | |
| Guinea | 470 | 78 | 1279 | 4.44 | 4.44–4.44 | 3.89 | 3.88–3.89 | 36.50 | 36.48–36.52 | 39.87 | 39.85–39.89 | |
| Uganda | 680 | 9 | 2116 | 38.13 | 38.11–38.15 | 23.81 | 23.80–23.82 | 35.42 | 35.40–35.43 | 58.39 | 58.33–58.46 | |
| South Sudan | 940 | 117 | 2397 | 34.00 | 33.98–34.02 | 21.59 | 21.58–21.61 | 33.08 | 33.06–33.11 | 41.25 | 41.21–41.29 | |
| Chad | 980 | 195 | 946 | 8.80 | 8.79–8.80 | 5.66 | 5.66–5.66 | 10.53 | 10.52–10.53 | 12.58 | 12.57–12.59 | |
| Cameroon | 1360 | 6 | 221 | 0.67 | 0.67–0.67 | 0.7 | 0.70–0.70 | 8.83 | 8.82–8.83 | 9.33 | 9.33–9.34 | |
| Cote d'Ivoire | 1460 | 7 | 1300 | 5.46 | 5.46–5.46 | 4.52 | 4.51–4.52 | 37.43 | 37.41–37.45 | 41.58 | 41.55–41.60 | |
| Republic of the Congo | 2710 | 20 | 2380 | 17.01 | 17.00–17.02 | 11.53 | 11.52–11.53 | 40.16 | 40.14–40.18 | 48.29 | 48.26–48.32 | |
| Nigeria | 2970 | 0 | 468 | 0.01 | 0.01–0.01 | 1.07 | 1.07–1.07 | 30.48 | 30.47–30.50 | 30.48 | 30.47–30.50 | |
| Angola | 4850 | 69 | 4300 | 59.15 | 59.11–59.19 | 38.85 | 38.83–38.88 | 93.86 | 93.81–93.91 | 107.36 | 107.28–107.43 | |
| Gabon | 9450 | 17 | 878 | 0.61 | 0.61–0.61 | 0.76 | 0.76–0.76 | 11.30 | 11.29-11-31 | 11.68 | 11.67–11.68 | |
| Equatorial Guinea | 12 640 | 3 | 31 | 0.75 | 0.75–0.75 | 0.47 | 0.47–0.47 | 0.69 | 0.69–0.69 | 1.17 | 1.17–1.17 | |
Blue indicatescountries that can afford the Elimination programme using GNI as cost-effectiveness threshold.
*Includes countries with endemic cases from 2000 to 2014 reported inFranco et al.37
†Net budget impact compared to ‘Control’.
‡Includes 13 endemic countries in 2013, excluding Ghana.
§Includes UMIC and one HIC (Equatorial Guinea GNI greater than USD 12 236).
.CAR, Central African Republic;DALY, disability adjusted life years; DRC, Democratic Republic of Congo; GNI, gross national income; HAT Tbg, human African trypanosomiasis Trypanosoma brucei gambiense; HIC, high-income country; LMIC, low-income country and middle-income country; NA, not applicable; UMIC, upper-middle income country; USD, US dollar.