Table 3

Estimated direct societal cost of antibiotic resistance per antibiotic prescribed for the outpatient management of ARTIs in Sri Lanka, estimated in US$

RowInputs and outputsBase caseLowHighSource
Input
 aAnnual total cost of antibiotic resistance$229 120 600$114 560 300$343 680 90014 34 67–69
 bAntibiotics prescribed to humans versus animals97.6%48.8%100%32 33 35
 cImpact of human versus animal antibiotic use on societal cost of resistance200%*100%300%14
 dAntibiotics prescribed in outpatient setting80%*40%100%14
 eOutpatient care occurring in public sector40%20%60%39
 fPercentage of outpatient visits that are for ARTIs10.5%5.3%15.8%40
 gAnnual antibiotic prescriptions35 920 82535 920 82535 920 2536
 h=abcdefAnnual excess costs of antibiotic resistance attributable to outpatient antibiotic prescribing for ARTIs in the public sector$15 027 379$237 039$97 742 848
 i=(abc)/gAnnual excess costs of antibiotic resistance per antibiotic prescribed in the outpatient public sector for management of ARTIs (US$)$12.5$1.6$28.7
  • *Estimate from Michaelidis et al14 used given lack of data for Sri Lanka.

  • ARTIs, acute respiratory tract infections.