Row | Inputs and outputs | Base case | Low | High | Source |
Input | |||||
a | Annual total cost of antibiotic resistance | $229 120 600 | $114 560 300 | $343 680 900 | 14 34 67–69 |
b | Antibiotics prescribed to humans versus animals | 97.6% | 48.8% | 100% | 32 33 35 |
c | Impact of human versus animal antibiotic use on societal cost of resistance | 200%* | 100% | 300% | 14 |
d | Antibiotics prescribed in outpatient setting | 80%* | 40% | 100% | 14 |
e | Outpatient care occurring in public sector | 40% | 20% | 60% | 39 |
f | Percentage of outpatient visits that are for ARTIs | 10.5% | 5.3% | 15.8% | 40 |
g | Annual antibiotic prescriptions | 35 920 825 | 35 920 825 | 35 920 25 | 36 |
h=abcdef | Annual excess costs of antibiotic resistance attributable to outpatient antibiotic prescribing for ARTIs in the public sector | $15 027 379 | $237 039 | $97 742 848 | |
i=(abc)/g | Annual excess costs of antibiotic resistance per antibiotic prescribed in the outpatient public sector for management of ARTIs (US$) | $12.5 | $1.6 | $28.7 |
*Estimate from Michaelidis et al14 used given lack of data for Sri Lanka.
ARTIs, acute respiratory tract infections.