Table 2

Interrupted time series analysis parameters of the total volume for referent and bioequivalent medicines

Active pharmaceutical ingredientReferentBioequivalents
Estimate95% CIP valueEstimate95% CIP value
Total trend
 Level before the intervention (Embedded Image )4916.84786.3 to 5047.30.002142.81767.8 to 2517.70.00
 Trend before the intervention (Embedded Image )10.11.65 to 18.610.0228.080.8 to 55.40.04
 Level change after the intervention (Embedded Image )518.5302.78 to 734.2 0.00 −58.3−722.3 to 605.70.86
 Trend change after the intervention (Embedded Image )−26.7−40.7 to −12.8 0.00 −9.7−48.7 to 29.40.62
  • We are considering a p value less than 0.05 as a statistically significant value. Bold means p value <0.05.

  • Units used in this analysis are the number of daily defined doses of the active pharmaceutical ingredients included.