Table 6

Ratio of median prices between the bioequivalents and the referent in 2011 and 2016 shown as percentage (the difference between 2011 and 2016 is also shown)

Active pharmaceutical ingredient (1)Median price ratio BEQ:referent (2011) (2)Median price ratio BEQ:referent (2016) (3)Difference between ratio in 2016 and the ratio in 2011 (4)
Group 1
 Ciclosporin85.7%66.1%−19.6%
 Verapamil46.1%57.8%11.7%
 Tacrolimus81.9%66.4%−15.5%
 Clomipramine49.5%45.7%−3.9%
 Acenocoumarol38.7%44.5%5.8%
 Mycophenolate mofetil59.3%48.7%−10.6%
 ZidovudineBEQ not soldReferent not sold
Group 2
 Atorvastatin56.1%38.0%−18.0%
 Cefadroxil86.4%87.9%1.5%
 Doxycycline63.3%57.9%−5.3%
 Losartan47.4%43.4%−4.0%
 Ketoprofen34.9%49.6%14.7%
 Levothyroxine48.0%75.1%27.1%
 Prednisone50.4%Referent not sold
 Metformin73.0%76.2%3.3%
 Clonazepam71.2%64.9%−6.3%
  • BEQ, bioequivalent.