Optimal WC to predict insulin resistance (IR) by HOMA-IR and Matsuda index
| Sex | WC | IR by HOMA-IR | IR by Matsuda Index | ||||||||
| AUC-ROC*±SE (95% CI) | Youden index | Sensitivitiy (%) | Specificity (%) | BMI* | AUC-ROC±SE (95% CI)† | Youden index | Sensitivity (%) | Specificity (%) | BMI* | ||
| Part A: men | WC1‡ | 0.80±0.03 (0.74 to 0.86) | 91 cm | 89 | 63 | 27.3 | 0.82±0.03 (0.77, 0.88) | 91 cm | 95 | 59 | 27.3 |
| WC2§ | 0.79±0.03 (0.74 to 0.85) | 92 cm | 84 | 67 | 27.6 | 0.82±0.03 (0.76, 0.88) | 91 cm | 88 | 66 | 27.3 | |
| Part B: women | WC1‡ | 0.81±0.08 (0.72 to 0.90) | 96 cm | 67 | 87 | 30.6 | 0.75±0.05 (0.64, 0.85) | 96 cm | 59 | 84 | 30.6 |
| WC2§ | 0.83±0.05 (0.74 to 0.92) | 95 cm | 67 | 89 | 30.3 | 0.80±0.06 (0.69, 0.90) | 95 cm | 64 | 86 | 30.5 | |
*Linear regression formula for body mass index (BMI) predicted by waist circumference (WC): men: BMI=−2.76+0.33*WC; women: BMI=−3.95+0.36*WC.
†Area under the receiver operating characteristic curve (AUC-ROC).
‡WC according to NHANES protocol.
§WC according to WHO protocol.