Table 1

Potential burden of latent tuberculosis infection among household members by antituberculosis drug resistance profile, India—2016

DST resultProportion with DST profileEstimated number of TB index casesEstimated number of household tuberculosis infections
n (95% confidence limits)*n (95% CI)†n (95% CI)‡§
Drug susceptible72.0 (70.7 to 73.2)1 263 569 (1 240 755 to 1 284 629)3 032 566 (2 977 812 to 3 083 110)
Any resistance to isoniazid11.1 (10.3 to 12.4)194 800 (180 761 to 217 615)467 520 (433 826 to 522 276)
Any resistance to rifampicin6.2 (5.5 to 6.9)108 807 (96 523 to 121 092)261 137 (261 137 to 290 621)
Any resistance to fluoroquinolone5.1 (4.5 to 5.8)89 503 (78 973 to 101 788)214 807 (189 535 to 244 291)
Total 3 976 030 (3 862 310 to 4 140 298)
  • *Source data: Ministry of Health and Family Welfare. Government of India. Report of the first nationwide antituberculosis drug resistance survey—India, 20142015. 70

  • †Revised National Tuberculosis Control Programme Case Reporting Data, 2016. N=1 754 957.30

  • ‡Office of the Registrar General and Census Commissioner, India. HH-01. Normal Households by Household Size. Mean household size=4.8.31

  • §Assumes 50% latent tuberculosis infection rate.10 ,25–29

  • DST, drug susceptibility testing.