Number assigned (n=459) and specificity of VA methods in assigning HIV-associated causes of death, compared with confirmed (n=103) and VA-reported (n=153) HIV status
VA method | Number assigned an HIV-associated CoD, n (CSMF; %/459) | Specificity of VA method | |
Based on confirmed serostatus (95% CI)* | Based on VA-reported HIV status (95% CI)† | ||
PCVA | 287 (62.5) | 96.1 (90.4 to 98.9) | 81.0 (73.9 to 86.9) |
InterVA-4.03‡ | (37.1) | 89.3 (81.7 to 94.5)§ | 83.0 (76.1 to 88.6)§ |
InterVA-5‡ | (44.9) | 87.4 (79.4 to 93.1)§ | 78.4 (71.1 to 84.7)§ |
SmartVA-Analyze V.1.1.1 | 85 (18.5) | 95.1 (89.0 to 98.4) | 90.2 (84.3 to 94.4) |
SmartVA-Analyze V.1.2.1 | 294 (64.1) | 95.1 (89.0 to 98.4) | 97.4 (93.4 to 99.3) |
*n=103 individuals confirmed HIV negative.
†n=153 individuals reported HIV negative or with HIV status unknown.
‡InterVA-4 and InterVA-5 CSMFs calculated from all assigned CoD with associated likelihoods.
§Individuals considered ‘test positive’ if HIV/AIDS assigned as most likely CoD (n=177 for InterVA-4; n=214 for InterVA-5).
CoD, cause of death; CSMF, cause-specific mortality fraction; PCVA, physician-certified verbal autopsy; VA, verbal autopsy.