Table 4

Number assigned (n=459) and specificity of VA methods in assigning HIV-associated causes of death, compared with confirmed (n=103) and VA-reported (n=153) HIV status

VA methodNumber assigned an HIV-associated CoD, n (CSMF; %/459)Specificity of VA method
Based on confirmed serostatus (95% CI)*Based on VA-reported HIV status (95% CI)†
PCVA287 (62.5)96.1 (90.4 to 98.9)81.0 (73.9 to 86.9)
InterVA-4.03‡(37.1)89.3 (81.7 to 94.5)§83.0 (76.1 to 88.6)§
InterVA-5‡(44.9)87.4 (79.4 to 93.1)§78.4 (71.1 to 84.7)§
SmartVA-Analyze V.1.1.185 (18.5)95.1 (89.0 to 98.4)90.2 (84.3 to 94.4)
SmartVA-Analyze V.1.2.1294 (64.1)95.1 (89.0 to 98.4)97.4 (93.4 to 99.3)
  • *n=103 individuals confirmed HIV negative.

  • †n=153 individuals reported HIV negative or with HIV status unknown.

  • ‡InterVA-4 and InterVA-5 CSMFs calculated from all assigned CoD with associated likelihoods.

  • §Individuals considered ‘test positive’ if HIV/AIDS assigned as most likely CoD (n=177 for InterVA-4; n=214 for InterVA-5).

  • CoD, cause of death; CSMF, cause-specific mortality fraction; PCVA, physician-certified verbal autopsy; VA, verbal autopsy.