Table 2

Net DALYs averted at full and actual implementation levels

Intervention(1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)
ICER rankingICER ($)Pop. DALYs averted per 1000Cases per annum (1000 s)Actual imp. levelTotal cost (full imp.; $1000s)Total cost (actual imp.; $1000s)Total DALYs averted (full imp.; 1000s)Total DALYs averted (actual imp.; 1000s)Net DALYs averted (full imp.; 1000s)Net DALYs averted actual imp.; 1000s)Financial value to the healthcare system of moving from actual to full imp. ($1000s)
Male circumcision382245407312%146 73017 60839 634475625 42330511 372 314
Isoniazid preventive therapy for HIV+ no (TB)418875550%80401118559109854933 673
First-line treatment for new TB cases for adults533931464%1781141045669100264122 122
First-line treatment for new TB cases for children733931264%1177588856885154518 789
Clean practices and immediate essential newborn care (home)933686710%41623722713 909
Management of pre-eclampsia (magnesium sulfate)2361682080%45365354284833865923
Voluntary counselling and testing412540803115%36 30954461672598155120
Rotavirus vaccine2261776510%309788804920
Households owning at least one ITN/LLIN331377675256%13 73777062281281801014847
Malaria treatment: first trimester—uncomplicated19519830533%102534110936100334087
PMTCT2711945355%60033215787130723561
Malaria treatment: uncomplicated—second line (adult, >36 kg)13426043722%1186185915613354
Malaria treatment: uncomplicated—second line (adult, <36 kg)14426043724%593215925623285
Labour and delivery management28118991865%1281833170111139912992
First-line treatment for retreatment TB cases for adults63393265%1006513185125812688
Mass media2190316 87971%760954021501071481052627
Malaria treatment: uncomplicated (adult, <36 kg)114260437230%34631039591856172383
Interventions focused on men who have sex with men485120345%125663232124022311
Antenatal care (four visits)36156891846%11 2305110904168312289
First-line treatment for retreatment TB cases for children83393265%664311172106692283
Malaria treatment: second trimester—uncomplicated20519830567%23515710972100672047
Antenatal corticosteroids for preterm labour4025401650%40647281718
Newborn sepsis— full supportive care3924428140%417167602437151346
Cotrimoxazole for children1cost saving12713%22028002331208
Interventions focused on female sex workers4751202330%655197161482881184
Vaginal delivery, skilled attendance31128391865%51813368674354351153
Malaria treatment: uncomplicated (adult, >36 kg)124260437270%42672987594156391021
Tetanus toxoid (pregnant women)24714991884%11596104879277905
Malaria treatment: uncomplicated—second line (children, <15 kg)17426010422%351140130799
Malaria treatment: uncomplicated—second line (children,>15 kg)18426010424%712140130783
Schistosomiasis mass drug administration42293538913%7710243132670
Vitamin A supplementation in pregnant women25714012465%1258133223019634
Malaria treatment: uncomplicated (children, >15 kg)164260104240%47681907146135487
Antibiotics for pPRoM4540256430%3912309103450
Maternal sepsis case management443926640%2731207449
Management of severe malnutrition (children)4650205180%243719491991593629446
Isoniazid preventive therapy for children in contact with patients with TB31900285%7645384438408
Malaria treatment: uncomplicated (children, <15 kg)154260104260%45762746148138325
Vaginal delivery, with complication32128313851%80441010584242
Measles vaccine26910665199%528523107106908955
Management of obstructed labour30128692100%110011002497249720262026
Caesarean section43323134100%672672327327157157
Caesarean section (with complication)2912865100%172172137137111111
Pregnant women sleeping under an ITN3413771469100%2990299050503939
Under five children who slept under ITN/LLIN351377494100%1006100617171313
Blood safety37156640100%16261626121299
Malaria treatment: pregnant women— complicated21519816100%1401406655
Case management of MDR TB cases1032970100%12125555
Malaria treatment: pregnant women—complicated21519816100%1401406655
Caesarean section (with complication)2912865100%172172137137111111
Management of obstructed labour30128692100%110011002497249720262026
Pregnant women sleeping under an ITN3413771469100%2990299050503939
Under five children who slept under ITN/LLIN351377494100%1006100617171313
Blood safety37156640100%16261626121299
Caesarean section43323134100%672672327327157157
IPT (pregnant women)521109735100%353500−0−0
GIT cancer638041050%3100−0−0−0
Cervical cancer (first line)6510871250%1628100−0−0−0
Ischaemic heart disease61453212815%4100−0−0−2
Diabetes, type I5729632315%430464600−0−0−5
High cholesterol4968152231%67036710−0−0−6
Basic psychosocial support, advice and follow-up, plus antiepileptic medication5082125063%12663810−0−0−14
Treatment of depression5626541691%332300−0−0−23
Diabetes, Type II58296313815%421163200−1−0−30
Treatment of acute psychotic disorders66164611691%9581000−1−0−42
Treatment of bipolar disorder6255725233%10 36232100−1−0−87
Treatment of schizophrenia6716461236314%13 413187800−10−1−512
Hypertension55159684610%1338134444−71−7−3912
ORS541537866269%937647147102−221−152−4197
Zinc (diarrhoea treatment)51991074550%1788244−150−9207
Condoms531278803147%22 88310 755482226−517−243−16 813
ART for men59312333275%21 15915 9611005758−4104−3,096−61 848
ART for women60312350982%32 44026 66915411267−6292−5,173−68 665
Paediatric ART64892110725%765718921556384−21 074−5,206−973 334
  • ART, antiretroviral therapy; DALY, disability adjusted life year; GIT, gastrointestinal; ICER, incremental cost effectiveness ratio; IPT, intermittent preventive therapy; ITN, insecticide-treated bed net; LLIN, long-lasting insecticidal net; MDR, multidrug resistant; ORS, oral rehydration salts; PMTCT, prevention of mother to child transmission; pPRoM, preterm premature rupture of membranes; TB, tuberculosis.