Comparison of baseline demographic characteristics among Guatemalan children enrolled in PTM202 Diarrhoeal Treatment Trial: urban versus rural study sites
| Variable | Urban | Rural | P value |
| Age (months) * | 16.5 (6.8) | 18.7 (7.8) | 0.007 |
| Height (cm) * | 77.6 (7.1) | 77.0 (6.9) | 0.45 |
| Weight at enrolment (kg) * | 9.4 (1.7) | 8.8 (1.6) | 0.005 |
| Weight-for-age WHO z-score at enrolment* | −0.8 (1.0) | −1.6 (1.1) | <0.0001 |
| Weight for length at enrolment* | −0.7 (1.0) | −1.2 (1.0) | <0.0001 |
| Estimated per cent dehydration at enrolment*† | 0.02% (3.5%) | 0.93% (4.1%) | 0.03 |
| Sex‡ | |||
| Female | 65 (45.0%) | 82 (47.7%) | 0.73 |
| Male | 79 (55.0%) | 90 (52.3%) | |
| Intervention‡ | |||
| PTM202 | 76 (52.8%) | 86 (50.0%) | 0.65 |
| Placebo | 68 (47.2%) | 86 (50.0%) | |
| Water supply to house‡ | |||
| Public or bottled water | 135 (93.8%) | 19 (11.1%) | <0.0001 |
| Rain water or water tank | 6 (4.2%) | 1 (0.6%) | |
| Well or river | 3 (2.1%) | 152 (88.4%) | |
| Method of human waste disposal‡ | |||
| Indoor plumbing (toilet) | 136 (94.4%) | 32 (18.6%) | 0.0001 |
| Latrine: open pit | 5 (3.5%) | 138 (80.2%) | |
| Latrine: septic tank | 3 (2.1%) | 2 (1.2%) | |
| Total pathogen count* | 2.7 (1.6) | 4.8 (1.8) | <0.0001 |
| Total number of directly targeted pathogens* | 0.5 (0.7) | 0.9 (0.7) | <0.0001 |
| Total number of directly and indirectly targeted pathogens* | 1.0 (0.9) | 1.7±1.0 | <0.0001 |
| Total number of bacteria* | 1.8 (1.4) | 3.3±1.4 | <0.0001 |
| Total number of parasites* | 0.1 (0.4) | 0.7±0.6 | <0.0001 |
| Total number of viruses* | 0.7 (0.7) | 0.8±0.7 | 0.98 |
*Estimates for symmetrical numeric variables given as mean±SD per case.
†Estimate based on % weight change from enrolment to 48 hours rehydrated weight.
‡Estimates for categorical variables given as frequency (%).