Estimates of infection attack rate (IAR) of viruses transmitted by Aedes mosquitoes following epidemics in populations that were presumably immunologically naïve to these viruses prior to each epidemic in the Americas. These IAR estimates were used to allow for validation of the model against independent IAR estimates.
| IAR | Virus | Location | Possible vector species involved | Ref. |
| 0.64 | ZIKV | Recife, Brazil | Ae. aegypti | 40 |
| 0.50 | ZIKV | Guayaquil, Ecuador | Ae. aegypti | 42 |
| 0.25 | CHIKV | Puerto Rico, USA | Ae. aegypti | 41 |
| 0.20 | CHIKV | Chapada, Brazil | Ae. aegypti | 39 |