Population characteristics of patients pooled from hospital-based cohort studies conducted in six African countries from 2009 to 2015 according to outcomes
| Variable | Overall (n=5573) | Survived (n=4607) | Died in-hospital (n=966) | p |
| Female, n (%) | 2829 (50.8) | 2323 (50.4) | 506 (52.4) | 0.27 |
| Age (years), median (IQR) | 36 (27–49) | 36 (26–50) | 36 (29–46) | 0.20 |
| Temperature (°C), median (IQR) | 37.4 (36.3–38.5) | 37.4 (36.3–38.5) | 37.6 (36.2–38.4) | 0.36 |
| Heart rate (bpm), median (IQR) | 100 (85–120) | 100 (84–116) | 110 (92–128) | <0.001 |
| Respiratory rate (brpm), median (IQR) | 26 (22–32) | 24 (20–32) | 30 (24–40) | <0.001 |
| SBP (mm Hg), median (IQR) | 100 (90–120) | 100 (90–120) | 90 (80–110) | <0.001 |
| DBP (mm Hg), median (IQR) | 62 (55–80) | 65 (60–80) | 60 (50–70) | <0.001 |
| Oxygen saturation (%), median (IQR) | 96 (94–98) | 96 (94–98) | 96 (93–98) | <0.001 |
| GCS score, median (IQR) | 15 (15–15) | 15 (15–15) | 15 (13–15) | <0.001 |
| HIV-infected, n (%) | 2122 (38.1) | 1537 (33.4) | 585 (60.1) | <0.001 |
| CD4 (cells/μL), median (IQR) | 72 (23–156) | 79 (28–175) | 46 (14–112) | <0.001 |
| WBC (103/μL), median (IQR) | 6.0 (3.7–9.7) | 6.1 (3.9–9.7) | 5.6 (3.1–9.7) | 0.003 |
| Haemoglobin (g/dL), median (IQR) | 10.1 (7.8–12.2) | 10.4 (8.1–12.5) | 8.7 (6.9–11.2) | <0.001 |
| Platelets (103/μL), median (IQR) | 180 (105–270) | 188 (113–275) | 159 (81–256) | <0.001 |
| Lactate (mmol/L), median (IQR) | 3.5 (2.4–4.9) | 3.3 (2.4–4.5) | 4.2 (2.7–6.1) | <0.001 |
bpm, beats per minute; brpm, breaths per minute; CD, cluster of differentiation; DBP, diastolic blood pressure; GCS, Glasgow Coma Scale; SBP, systolic blood pressure; WBC, white blood cell concentration.